Prolonged dysregulation and pathological changes in the upper respiratory tract of SARS-CoV-2 infected hamsters.

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Title: Prolonged dysregulation and pathological changes in the upper respiratory tract of SARS-CoV-2 infected hamsters.
Authors: Liu F; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China., Xia Y; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China.; School of Biomedical Science, Microbiology and Immunology, The University of Western Australia, Perth, WA, Australia., Lee AC; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong SAR, China., Chen Y; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong SAR, China., Chen Z; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China., He Y; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China., Chan CH; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China., Cai J; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China., Yuen TT; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong SAR, China., Ye ZW; School of Biomedical Sciences, The University of Hong Kong, Hong Kong SAR, China., Zhang J; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong SAR, China., Qian Z; MOE Key Laboratory of Pathogen Infection Prevention and Control, Peking Union Medical College, Beijing, China.; NHC Key Laboratory of Systems Biology of Pathogens, National Institute of Pathogen Biology, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China.; State Key Laboratory of Respiratory Health and Multimorbidity, Chinese Academy of Medical Sciences & Peking Union Medical College, Beijing, China., Yuen KY; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong SAR, China.; Department of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong Province, China.; Department of Microbiology, Queen Mary Hospital, Hong Kong SAR, China.; Academician Workstation of Hainan Province, Hainan Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, Haikou, Hainan Province, China.; Pandemic Research Alliance Unit at The University of Hong Kong, Hong Kong SAR, China., Chan JF; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong SAR, China.; Department of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong Province, China.; Department of Microbiology, Queen Mary Hospital, Hong Kong SAR, China.; Academician Workstation of Hainan Province, Hainan Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, Haikou, Hainan Province, China.; Pandemic Research Alliance Unit at The University of Hong Kong, Hong Kong SAR, China., Chu H; Department of Microbiology, Li Ka Shing Faculty of Medicine, State Key Laboratory of Emerging Infectious Diseases, School of Clinical Medicine, The University of Hong Kong, Hong Kong SAR, China. hinchu@hku.hk.; Centre for Virology, Vaccinology and Therapeutics, Hong Kong Science and Technology Park, Hong Kong SAR, China. hinchu@hku.hk.; Department of Infectious Disease and Microbiology, The University of Hong Kong-Shenzhen Hospital, Shenzhen, Guangdong Province, China. hinchu@hku.hk.; Academician Workstation of Hainan Province, Hainan Medical University-The University of Hong Kong Joint Laboratory of Tropical Infectious Diseases, Haikou, Hainan Province, China. hinchu@hku.hk.; Pandemic Research Alliance Unit at The University of Hong Kong, Hong Kong SAR, China. hinchu@hku.hk.; Materials Innovation Institute for Life Sciences and Energy (MILES), HKU-SIRI, Shenzhen, China. hinchu@hku.hk.
Source: Npj viruses [Npj Viruses] 2026 Mar 02; Vol. 4 (1). Date of Electronic Publication: 2026 Mar 02.
Publication Type: Journal Article
Journal Info: Publisher: Nature Portfolio, Springer Nature Country of Publication: England NLM ID: 9918716188906676 Publication Model: Electronic Cited Medium: Internet ISSN: 2948-1767 (Electronic) Linking ISSN: 29481767 NLM ISO Abbreviation: Npj Viruses Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2948-1767
DOI:10.1038/s44298-026-00181-w