New Multitarget Inhibitor Potentiates Antimicrobial Activity of Aztreonam against Metallo-β-lactamase-Producing Pseudomonas aeruginosa Including IMP-Types.
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| Title: | New Multitarget Inhibitor Potentiates Antimicrobial Activity of Aztreonam against Metallo-β-lactamase-Producing Pseudomonas aeruginosa Including IMP-Types. |
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| Authors: | Kang J; Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Neungdong-ro 120, Gwangjin-gu, Seoul 05029, Korea., Lee D; Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Neungdong-ro 120, Gwangjin-gu, Seoul 05029, Korea., Kim MK; Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Neungdong-ro 120, Gwangjin-gu, Seoul 05029, Korea., Ahn JH; Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Neungdong-ro 120, Gwangjin-gu, Seoul 05029, Korea., Kim TW; College of Veterinary Medicine (BK21 FOUR Program), Chungnam National University, 99 Daehak-ro, Daejeon 34131, Republic of Korea., Park J; Infectious Disease Research Center, Korea Research Institute of Bioscience & Biotechnology, Daejeon 34141, Korea., Seo HW; Infectious Disease Research Center, Korea Research Institute of Bioscience & Biotechnology, Daejeon 34141, Korea., Ahn TK; Department of Regulatory Science, Institutes of Regulatory Innovation through Science and Integrated Pharmaceutical Sciences, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea., Chung EK; Departments of Pharmacy and Regulatory Science, Institutes of Regulatory Innovation through Science (IRIS) and Integrated Pharmaceutical Sciences, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea., Park KH; Department of Infectious Disease, Kyung Hee University School of Medicine, Seoul 02447, Republic of Korea., Chong Y; Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Neungdong-ro 120, Gwangjin-gu, Seoul 05029, Korea. |
| Source: | Journal of medicinal chemistry [J Med Chem] 2026 Mar 12; Vol. 69 (5), pp. 5560-5574. Date of Electronic Publication: 2026 Mar 03. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Chemical Society Country of Publication: United States NLM ID: 9716531 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1520-4804 (Electronic) Linking ISSN: 00222623 NLM ISO Abbreviation: J Med Chem Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| FullText | Text: Availability: 0 |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41773615 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: New Multitarget Inhibitor Potentiates Antimicrobial Activity of Aztreonam against Metallo-β-lactamase-Producing Pseudomonas aeruginosa Including IMP-Types. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Kang+J%22">Kang J</searchLink>; Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Neungdong-ro 120, Gwangjin-gu, Seoul 05029, Korea.<br /><searchLink fieldCode="AU" term="%22Lee+D%22">Lee D</searchLink>; Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Neungdong-ro 120, Gwangjin-gu, Seoul 05029, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+MK%22">Kim MK</searchLink>; Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Neungdong-ro 120, Gwangjin-gu, Seoul 05029, Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+JH%22">Ahn JH</searchLink>; Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Neungdong-ro 120, Gwangjin-gu, Seoul 05029, Korea.<br /><searchLink fieldCode="AU" term="%22Kim+TW%22">Kim TW</searchLink>; College of Veterinary Medicine (BK21 FOUR Program), Chungnam National University, 99 Daehak-ro, Daejeon 34131, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Park+J%22">Park J</searchLink>; Infectious Disease Research Center, Korea Research Institute of Bioscience & Biotechnology, Daejeon 34141, Korea.<br /><searchLink fieldCode="AU" term="%22Seo+HW%22">Seo HW</searchLink>; Infectious Disease Research Center, Korea Research Institute of Bioscience & Biotechnology, Daejeon 34141, Korea.<br /><searchLink fieldCode="AU" term="%22Ahn+TK%22">Ahn TK</searchLink>; Department of Regulatory Science, Institutes of Regulatory Innovation through Science and Integrated Pharmaceutical Sciences, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.<br /><searchLink fieldCode="AU" term="%22Chung+EK%22">Chung EK</searchLink>; Departments of Pharmacy and Regulatory Science, Institutes of Regulatory Innovation through Science (IRIS) and Integrated Pharmaceutical Sciences, College of Pharmacy, Kyung Hee University, Seoul 02447, Korea.<br /><searchLink fieldCode="AU" term="%22Park+KH%22">Park KH</searchLink>; Department of Infectious Disease, Kyung Hee University School of Medicine, Seoul 02447, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Chong+Y%22">Chong Y</searchLink>; Department of Bioscience and Biotechnology, Bio/Molecular Informatics Center, Konkuk University, Neungdong-ro 120, Gwangjin-gu, Seoul 05029, Korea. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%229716531%22">Journal of medicinal chemistry</searchLink> [J Med Chem] 2026 Mar 12; Vol. 69 (5), pp. 5560-5574. <i>Date of Electronic Publication: </i>2026 Mar 03. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22American+Chemical+Society%22">American Chemical Society </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>9716531 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1520-4804 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2200222623%22">00222623 </searchLink><i>NLM ISO Abbreviation: </i>J Med Chem <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41773615 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1021/acs.jmedchem.5c02664 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: 5560 Titles: – TitleFull: New Multitarget Inhibitor Potentiates Antimicrobial Activity of Aztreonam against Metallo-β-lactamase-Producing Pseudomonas aeruginosa Including IMP-Types. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Kang J – PersonEntity: Name: NameFull: Lee D – PersonEntity: Name: NameFull: Kim MK – PersonEntity: Name: NameFull: Ahn JH – PersonEntity: Name: NameFull: Kim TW – PersonEntity: Name: NameFull: Park J – PersonEntity: Name: NameFull: Seo HW – PersonEntity: Name: NameFull: Ahn TK – PersonEntity: Name: NameFull: Chung EK – PersonEntity: Name: NameFull: Park KH – PersonEntity: Name: NameFull: Chong Y IsPartOfRelationships: – BibEntity: Dates: – D: 12 M: 03 Text: 2026 Mar 12 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1520-4804 Numbering: – Type: volume Value: 69 – Type: issue Value: 5 Titles: – TitleFull: Journal of medicinal chemistry Type: main |
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