TCR sequencing in cancer immunology and immunotherapy: what, when, where, why, and how.

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Title: TCR sequencing in cancer immunology and immunotherapy: what, when, where, why, and how.
Authors: Nose Y MD, PhD; Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Figueiredo I; Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Tuballes K; Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Del Valle DM PhD; Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Gonsalves TR; Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Guo R; Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Ioannou G; Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Cabal R MD; Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Gonzalez-Kozlova E PhD; Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA., Gnjatic S PhD; Immunology and Immunotherapy, Icahn School of Medicine at Mount Sinai, New York, New York, USA sacha.gnjatic@mssm.edu.; Tisch Cancer Institute, Icahn School of Medicine at Mount Sinai, New York, New York, USA.; Human Immune Monitoring Center, Icahn School of Medicine at Mount Sinai, New York, New York, USA.
Source: Journal for immunotherapy of cancer [J Immunother Cancer] 2026 Mar 03; Vol. 14 (3). Date of Electronic Publication: 2026 Mar 03.
Publication Type: Journal Article; Review
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101620585 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-1426 (Electronic) Linking ISSN: 20511426 NLM ISO Abbreviation: J Immunother Cancer Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2051-1426
DOI:10.1136/jitc-2025-013499