Risks of non-breast, non-ovarian cancers for BRCA1 and BRCA2 pathogenic variant carriers: a prospective cohort study.

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Title: Risks of non-breast, non-ovarian cancers for BRCA1 and BRCA2 pathogenic variant carriers: a prospective cohort study.
Authors: Yang R; Center for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, VIC, Australia.; Department of Epidemiology and Biostatistics, School of Public Health, Peking University Health Science Center, Beijing, China., MacInnis RJ; Center for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, VIC, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, East Melbourne, VIC, Australia., Milne RL; Center for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, VIC, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, East Melbourne, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Nguyen-Dumont T; Clinical Genomics, School of Translational Medicine, Monash University, Melbourne, VIC, Australia.; Department of Clinical Pathology, The University of Melbourne, Melbourne, VIC, Australia., Maxwell WF; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Genkinger JM; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, USA., Glendon G; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada., Ross EA; Biostatistics and Bioinformatics Facility, Fox Chase Cancer Center-Temple Health, Philadelphia, PA, USA., Andrulis IL; Lunenfeld-Tanenbaum Research Institute, Sinai Health System, Toronto, ON, Canada.; Department of Molecular Genetics, University of Toronto, Toronto, ON, Canada., Colonna SV; Huntsman Cancer Institute, University of Utah, Salt Lake City, UT, USA., Daly M; Fox Chase Cancer Center, Philadelphia, PA, USA., John EM; Department of Epidemiology & Population Health, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Kurian AW; Department of Epidemiology & Population Health, Stanford University School of Medicine, Stanford, CA, USA.; Department of Medicine, Stanford University School of Medicine, Stanford, CA, USA., Terry MB; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, USA.; Herbert Irving Comprehensive Cancer Center, Columbia University Irving Medical Center, New York, USA.; Silent Spring Institute, Newton, MA, USA., Hopper JL; Center for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, VIC, Australia., Southey MC; Center for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, VIC, Australia.; Cancer Epidemiology Division, Cancer Council Victoria, East Melbourne, VIC, Australia.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia., Phillips KA; Center for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, VIC, Australia.; Department of Medical Oncology, Peter MacCallum Cancer Centre, Melbourne, VIC, Australia.; Department of Oncology, Sir Peter MacCallum, University of Melbourne, Parkville, VIC, Australia., Li S; Center for Epidemiology and Biostatistics, Melbourne School of Population and Global Health, The University of Melbourne, Carlton, VIC, Australia. shuai.li@unimelb.edu.au.; Precision Medicine, School of Clinical Sciences at Monash Health, Monash University, Clayton, VIC, Australia. shuai.li@unimelb.edu.au.
Corporate Authors: Kathleen Cuningham Foundation Consortium for Research Into Familial Breast Cancer (kConFab)
Source: BMC medicine [BMC Med] 2026 Mar 04; Vol. 24 (1). Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190723 Publication Model: Electronic Cited Medium: Internet ISSN: 1741-7015 (Electronic) Linking ISSN: 17417015 NLM ISO Abbreviation: BMC Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1741-7015
DOI:10.1186/s12916-026-04753-8