Personalized pharmacokinetic-pharmacodynamic guided therapy via an induced pluripotent stem cell-derived multi-organoid platform in NF1-mutant breast cancer.
Saved in:
| Title: | Personalized pharmacokinetic-pharmacodynamic guided therapy via an induced pluripotent stem cell-derived multi-organoid platform in NF1-mutant breast cancer. |
|---|---|
| Authors: | Lim JH; Disease modeling and therapeutics team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.; Korea University of Science and Technology (UST), Daejeon, Republic of Korea., Mun SJ; Liver organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea., Kang HM; Disease modeling and therapeutics team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.; Korea University of Science and Technology (UST), Daejeon, Republic of Korea., Yu WD; Korea University of Science and Technology (UST), Daejeon, Republic of Korea.; Intestine organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea., Oh SJ; Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea., Lee JY; Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea., Son YS; Intestine organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea., Lee S; Korea University of Science and Technology (UST), Daejeon, Republic of Korea.; Digital Biotech Innovation Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea., Kim DS; Korea University of Science and Technology (UST), Daejeon, Republic of Korea.; Digital Biotech Innovation Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea., Lee J; Liver organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea., Kim SJ; Disease modeling and therapeutics team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.; Korea University of Science and Technology (UST), Daejeon, Republic of Korea., Cho HS; Disease modeling and therapeutics team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea. chohs@kribb.re.kr.; Korea University of Science and Technology (UST), Daejeon, Republic of Korea. chohs@kribb.re.kr., Son MJ; Korea University of Science and Technology (UST), Daejeon, Republic of Korea. mjson@kribb.re.kr.; Liver organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea. mjson@kribb.re.kr., Son MY; Korea University of Science and Technology (UST), Daejeon, Republic of Korea. myson@kribb.re.kr.; Intestine organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea. myson@kribb.re.kr., Jung CR; Disease modeling and therapeutics team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea. crjung@kribb.re.kr.; Korea University of Science and Technology (UST), Daejeon, Republic of Korea. crjung@kribb.re.kr. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Mar 05; Vol. 11 (1). Date of Electronic Publication: 2026 Mar 05. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| FullText | Links: – Type: pdflink Text: Availability: 1 |
|---|---|
| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41781386 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
| IllustrationInfo | |
| Items | – Name: Title Label: Title Group: Ti Data: Personalized pharmacokinetic-pharmacodynamic guided therapy via an induced pluripotent stem cell-derived multi-organoid platform in NF1-mutant breast cancer. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Lim+JH%22">Lim JH</searchLink>; Disease modeling and therapeutics team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.; Korea University of Science and Technology (UST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Mun+SJ%22">Mun SJ</searchLink>; Liver organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kang+HM%22">Kang HM</searchLink>; Disease modeling and therapeutics team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.; Korea University of Science and Technology (UST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Yu+WD%22">Yu WD</searchLink>; Korea University of Science and Technology (UST), Daejeon, Republic of Korea.; Intestine organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Oh+SJ%22">Oh SJ</searchLink>; Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea.; Department of Medical Science, Asan Medical Institute of Convergence Science and Technology, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+JY%22">Lee JY</searchLink>; Asan Institute for Life Sciences, Asan Medical Center, Seoul, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Son+YS%22">Son YS</searchLink>; Intestine organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+S%22">Lee S</searchLink>; Korea University of Science and Technology (UST), Daejeon, Republic of Korea.; Digital Biotech Innovation Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+DS%22">Kim DS</searchLink>; Korea University of Science and Technology (UST), Daejeon, Republic of Korea.; Digital Biotech Innovation Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Lee+J%22">Lee J</searchLink>; Liver organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Kim+SJ%22">Kim SJ</searchLink>; Disease modeling and therapeutics team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea.; Korea University of Science and Technology (UST), Daejeon, Republic of Korea.<br /><searchLink fieldCode="AU" term="%22Cho+HS%22">Cho HS</searchLink>; Disease modeling and therapeutics team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea. chohs@kribb.re.kr.; Korea University of Science and Technology (UST), Daejeon, Republic of Korea. chohs@kribb.re.kr.<br /><searchLink fieldCode="AU" term="%22Son+MJ%22">Son MJ</searchLink>; Korea University of Science and Technology (UST), Daejeon, Republic of Korea. mjson@kribb.re.kr.; Liver organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea. mjson@kribb.re.kr.<br /><searchLink fieldCode="AU" term="%22Son+MY%22">Son MY</searchLink>; Korea University of Science and Technology (UST), Daejeon, Republic of Korea. myson@kribb.re.kr.; Intestine organoid team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea. myson@kribb.re.kr.<br /><searchLink fieldCode="AU" term="%22Jung+CR%22">Jung CR</searchLink>; Disease modeling and therapeutics team, Stem cell Convergence Research Center, Korea Research Institute of Bioscience and Biotechnology (KRIBB), Daejeon, Republic of Korea. crjung@kribb.re.kr.; Korea University of Science and Technology (UST), Daejeon, Republic of Korea. crjung@kribb.re.kr. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101676423%22">Signal transduction and targeted therapy</searchLink> [Signal Transduct Target Ther] 2026 Mar 05; Vol. 11 (1). <i>Date of Electronic Publication: </i>2026 Mar 05. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101676423 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2059-3635 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220593635%22">20593635 </searchLink><i>NLM ISO Abbreviation: </i>Signal Transduct Target Ther <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41781386 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1038/s41392-026-02595-7 Languages: – Code: eng Text: English Titles: – TitleFull: Personalized pharmacokinetic-pharmacodynamic guided therapy via an induced pluripotent stem cell-derived multi-organoid platform in NF1-mutant breast cancer. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Lim JH – PersonEntity: Name: NameFull: Mun SJ – PersonEntity: Name: NameFull: Kang HM – PersonEntity: Name: NameFull: Yu WD – PersonEntity: Name: NameFull: Oh SJ – PersonEntity: Name: NameFull: Lee JY – PersonEntity: Name: NameFull: Son YS – PersonEntity: Name: NameFull: Lee S – PersonEntity: Name: NameFull: Kim DS – PersonEntity: Name: NameFull: Lee J – PersonEntity: Name: NameFull: Kim SJ – PersonEntity: Name: NameFull: Cho HS – PersonEntity: Name: NameFull: Son MJ – PersonEntity: Name: NameFull: Son MY – PersonEntity: Name: NameFull: Jung CR IsPartOfRelationships: – BibEntity: Dates: – D: 05 M: 03 Text: 2026 Mar 05 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 2059-3635 Numbering: – Type: volume Value: 11 – Type: issue Value: 1 Titles: – TitleFull: Signal transduction and targeted therapy Type: main |
| ResultId | 1 |
