FBXO39 knockdown promotes spermatogenesis impairment by inducing mitochondrial dysfunction and ferroptosis via inhibiting KDM5A ubiquitination and regulating H3K4me3 demethylation.
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| Title: | FBXO39 knockdown promotes spermatogenesis impairment by inducing mitochondrial dysfunction and ferroptosis via inhibiting KDM5A ubiquitination and regulating H3K4me3 demethylation. |
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| Authors: | Li T; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China., Wang K; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China., Chen Y; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China., Li Z; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China., Li S; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China., Zhang Y; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China., Zhu X; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China., Shi H; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China., Gao L; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China., Jiang H; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China. jht20032003@163.com. |
| Source: | Cell biology and toxicology [Cell Biol Toxicol] 2026 Mar 04; Vol. 42 (1). Date of Electronic Publication: 2026 Mar 04. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Country of Publication: Switzerland NLM ID: 8506639 Publication Model: Electronic Cited Medium: Internet ISSN: 1573-6822 (Electronic) Linking ISSN: 07422091 NLM ISO Abbreviation: Cell Biol Toxicol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41781602 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: FBXO39 knockdown promotes spermatogenesis impairment by inducing mitochondrial dysfunction and ferroptosis via inhibiting KDM5A ubiquitination and regulating H3K4me3 demethylation. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Li+T%22">Li T</searchLink>; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China.<br /><searchLink fieldCode="AU" term="%22Wang+K%22">Wang K</searchLink>; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China.<br /><searchLink fieldCode="AU" term="%22Chen+Y%22">Chen Y</searchLink>; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China.<br /><searchLink fieldCode="AU" term="%22Li+Z%22">Li Z</searchLink>; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China.<br /><searchLink fieldCode="AU" term="%22Zhang+Y%22">Zhang Y</searchLink>; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China.<br /><searchLink fieldCode="AU" term="%22Zhu+X%22">Zhu X</searchLink>; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China.<br /><searchLink fieldCode="AU" term="%22Shi+H%22">Shi H</searchLink>; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China.<br /><searchLink fieldCode="AU" term="%22Gao+L%22">Gao L</searchLink>; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China.<br /><searchLink fieldCode="AU" term="%22Jiang+H%22">Jiang H</searchLink>; The Department of Kidney Transplantation, The Second Affiliated Hospital of Hainan Medical University, 368 Yehai Road, Longhua District, Haikou City, 570216, Hainan Province, China. jht20032003@163.com. – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%228506639%22">Cell biology and toxicology</searchLink> [Cell Biol Toxicol] 2026 Mar 04; Vol. 42 (1). <i>Date of Electronic Publication: </i>2026 Mar 04. – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Springer%22">Springer </searchLink><i>Country of Publication: </i>Switzerland <i>NLM ID: </i>8506639 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1573-6822 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2207422091%22">07422091 </searchLink><i>NLM ISO Abbreviation: </i>Cell Biol Toxicol <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41781602 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1007/s10565-026-10167-2 Languages: – Code: eng Text: English Titles: – TitleFull: FBXO39 knockdown promotes spermatogenesis impairment by inducing mitochondrial dysfunction and ferroptosis via inhibiting KDM5A ubiquitination and regulating H3K4me3 demethylation. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Li T – PersonEntity: Name: NameFull: Wang K – PersonEntity: Name: NameFull: Chen Y – PersonEntity: Name: NameFull: Li Z – PersonEntity: Name: NameFull: Li S – PersonEntity: Name: NameFull: Zhang Y – PersonEntity: Name: NameFull: Zhu X – PersonEntity: Name: NameFull: Shi H – PersonEntity: Name: NameFull: Gao L – PersonEntity: Name: NameFull: Jiang H IsPartOfRelationships: – BibEntity: Dates: – D: 04 M: 03 Text: 2026 Mar 04 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1573-6822 Numbering: – Type: volume Value: 42 – Type: issue Value: 1 Titles: – TitleFull: Cell biology and toxicology Type: main |
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