LncRNA-PRLB drives ovarian cancer progression and chemoresistance by stabilizing GPX4 mRNA through the FUS-mediated suppression of ferroptosis.

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Title: LncRNA-PRLB drives ovarian cancer progression and chemoresistance by stabilizing GPX4 mRNA through the FUS-mediated suppression of ferroptosis.
Authors: Jiang L; Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan, China., Pi J; Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan, China., Li N; Department of Obstetrics and Gynecology, Jiayu County Maternal and Child Health Hospital, Jiayu, Hubei, China., Cao J; Department of Obstetrics and Gynecology, Wuhan Caidian District Maternal and Child Health Hospital of Wuhan, Wuhan, China., Zhao Y; Department of Obstetrics and Gynecology, Renmin Hospital of Wuhan University, Wuhan, China.
Source: Frontiers in medicine [Front Med (Lausanne)] 2026 Feb 17; Vol. 13, pp. 1759058. Date of Electronic Publication: 2026 Feb 17 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Media S.A Country of Publication: Switzerland NLM ID: 101648047 Publication Model: eCollection Cited Medium: Print ISSN: 2296-858X (Print) Linking ISSN: 2296858X NLM ISO Abbreviation: Front Med (Lausanne) Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2296-858X
DOI:10.3389/fmed.2026.1759058