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Fueling the fire: metabolic dysfunction and senescence as drivers of lung aging and disease.

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Title: Fueling the fire: metabolic dysfunction and senescence as drivers of lung aging and disease.
Authors: Kliment CR; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.; Department of Cellular and Molecular Pathology, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States., Gurkar AU; Aging Institute, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States.; Department of Medicine, Division of Geriatric Medicine, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States., Cárdenes N; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States., Ramonell RP; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States., Finkel T; Aging Institute, University of Pittsburgh Medical Center, University of Pittsburgh School of Medicine, Pittsburgh, Pennsylvania, United States., Königshoff M; Division of Pulmonary, Allergy, Critical Care and Sleep Medicine, Department of Medicine, University of Pittsburgh, Pittsburgh, Pennsylvania, United States.; Geriatric Research Education and Clinical Center (GRECC), Veterans Affairs Pittsburgh Healthcare System, Pittsburgh, Pennsylvania, United States.
Source: Physiological reviews [Physiol Rev] 2026 Jul 01; Vol. 106 (3), pp. 1535-1591. Date of Electronic Publication: 2026 Mar 06.
Publication Type: Journal Article; Review
Journal Info: Publisher: American Physiological Society Country of Publication: United States NLM ID: 0231714 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1522-1210 (Electronic) Linking ISSN: 00319333 NLM ISO Abbreviation: Physiol Rev Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1522-1210
DOI:10.1152/physrev.00024.2025