Cuproptosis-associated PDHA1 promotes sarcoma progression and immunotherapy responsiveness via the E2F1-PD-L1 axis: a multi-omics and clinical validation study.
Saved in:
| Title: | Cuproptosis-associated PDHA1 promotes sarcoma progression and immunotherapy responsiveness via the E2F1-PD-L1 axis: a multi-omics and clinical validation study. |
|---|---|
| Authors: | Qin H; Department of Orthopedics, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China.; Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China., Qi T; Department of Orthopedics, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China.; Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China., Yao N; Department of Pathology, Bengbu Medical University, Bengbu, Anhui, China., Sheng W; Department of Orthopedics, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China.; Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China., Deng J; Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China., Qian J; Department of Orthopedics, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China.; Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China., Wang D; Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China., Zeng H; Department of Orthopedics, Medical Innovation Technology Transformation Center of Shenzhen Second People's Hospital, Shenzhen Second People's Hospital, Shenzhen, Guangdong, China., Weng J; Department of Bone & Joint Surgery, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China. jweng@pku.edu.cn., Yang J; Department of Radiology, Peking University Shenzhen Hospital, Shenzhen, Guangdong, China. junyang@pkuszh.com., Yu F; Department of Spine Surgery, Shenzhen Second People's Hospital, The First Affiliated Hospital of Shenzhen University, Shenzhen, Guangdong, China. yufei89@pku.edu.cn. |
| Source: | NPJ precision oncology [NPJ Precis Oncol] 2026 Mar 06; Vol. 10 (1). Date of Electronic Publication: 2026 Mar 06. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Springer Nature Country of Publication: England NLM ID: 101708166 Publication Model: Electronic Cited Medium: Print ISSN: 2397-768X (Print) Linking ISSN: 2397768X NLM ISO Abbreviation: NPJ Precis Oncol Subsets: PubMed not MEDLINE |
| Database: | MEDLINE Ultimate |
|
Full text is not displayed to guests.
Login for full access.
|
|
| ISSN: | 2397-768X |
|---|---|
| DOI: | 10.1038/s41698-026-01298-0 |
