Inhibition of PADI2-mediated vimentin citrullination alleviates silica-induced pulmonary fibrosis in mice.

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Title: Inhibition of PADI2-mediated vimentin citrullination alleviates silica-induced pulmonary fibrosis in mice.
Authors: Jin F; School of Public Health, Hebei Key Laboratory for Organ Fibrosis Research, North China University of Science and Technology, Tangshan, China., Li Y; College of TCM, North China University of Science and Technology, Tangshan, 063210, Hebei Province, China., Li T; School of Public Health, Hebei Key Laboratory for Organ Fibrosis Research, North China University of Science and Technology, Tangshan, China., Liu S; School of Public Health, Hebei Key Laboratory for Organ Fibrosis Research, North China University of Science and Technology, Tangshan, China., Xu D; College of TCM, North China University of Science and Technology, Tangshan, 063210, Hebei Province, China., Liu H; School of Public Health, Hebei Key Laboratory for Organ Fibrosis Research, North China University of Science and Technology, Tangshan, China., Wei Z; School of Public Health, Hebei Key Laboratory for Organ Fibrosis Research, North China University of Science and Technology, Tangshan, China., Gao X; School of Public Health, Hebei Key Laboratory for Organ Fibrosis Research, North China University of Science and Technology, Tangshan, China.; NHC Key Laboratory of Pneumoconiosis, Department of Pulmonary and Critical Care Medicine, The First Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi province, China., Mao N; School of Public Health, Hebei Key Laboratory for Organ Fibrosis Research, North China University of Science and Technology, Tangshan, China., Cai W; School of Public Health, Hebei Key Laboratory for Organ Fibrosis Research, North China University of Science and Technology, Tangshan, China., Shi Y; NHC Key Laboratory of Pneumoconiosis, Department of Pulmonary and Critical Care Medicine, The First Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi province, China. chinasyw225@163.com., Zhang H; Department of Anesthesiology and Pain Medicine, Department of Physiology, Interdepartmental Division of Critical Care Medicine, University of Toronto, Toronto, ON, Canada. hzhaibozhang@gmail.com.; The Keenan Research Centre for Biomedical Science of St. Michael's Hospital, Toronto, ON, Canada. hzhaibozhang@gmail.com., Xu H; School of Public Health, Hebei Key Laboratory for Organ Fibrosis Research, North China University of Science and Technology, Tangshan, China. xuhong@ncst.edu.cn.; NHC Key Laboratory of Pneumoconiosis, Department of Pulmonary and Critical Care Medicine, The First Hospital of Shanxi Medical University, Taiyuan, 030001, Shanxi province, China. xuhong@ncst.edu.cn.; Health Science Center, North China University of Science and Technology, Tangshan, 063210, Hebei, China. xuhong@ncst.edu.cn.
Source: Particle and fibre toxicology [Part Fibre Toxicol] 2026 Mar 08; Vol. 23 (1). Date of Electronic Publication: 2026 Mar 08.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101236354 Publication Model: Electronic Cited Medium: Internet ISSN: 1743-8977 (Electronic) Linking ISSN: 17438977 NLM ISO Abbreviation: Part Fibre Toxicol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1743-8977
DOI:10.1186/s12989-026-00671-y