Harm outcomes applicable for most meta-analyses of randomized trials of biomedical interventions: a key concept in clinical epidemiology.

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Title: Harm outcomes applicable for most meta-analyses of randomized trials of biomedical interventions: a key concept in clinical epidemiology.
Authors: Christensen R; Section for Biostatistics and Evidence-Based Research, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark; Department of Clinical Research, Center of Rheumatic Research Odense (CERRO), University of Southern Denmark, Odense University Hospital, Odense, Denmark; Department of Clinical Research, Cochrane Denmark & Centre for Evidence-Based Medicine Odense (CEBMO), University of Southern Denmark, Odense, Denmark., Berthelsen DB; Section for Biostatistics and Evidence-Based Research, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark; Department of Clinical Research, Center of Rheumatic Research Odense (CERRO), University of Southern Denmark, Odense University Hospital, Odense, Denmark; Department of Rehabilitation, Municipality of Guldborgsund, Nykoebing F, Denmark. Electronic address: dorthe.bang.berthelsen@regionh.dk., Tugwell P; Department of Medicine and School of Epidemiology and Public Health Bruyere Research Institute, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada., Golder S; Department of Health Sciences, University of York, Heslington, UK., Qureshi R; Department of Ophthalmology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA., Mayo-Wilson E; Department of Epidemiology, UNC Gillings School of Global Public Health, Chapel Hill, NC, 27599, USA., Simon LS; SDG LLC Cambridge, MA, 02138, USA., Kwong J; Global Health Nursing, Graduate School of Nursing Science, St Luke's International University, Tokyo, Japan., Williamson PR; Department of Health Data Science, Medical Research Council-National Institute for Health and Care Research Trials Methodology Research Partnership, University of Liverpool, Liverpool, UK., Vohra S; Departments of Pediatrics and Psychiatry, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada.
Source: Journal of clinical epidemiology [J Clin Epidemiol] 2026 Jun; Vol. 194, pp. 112218. Date of Electronic Publication: 2026 Mar 07.
Publication Type: Journal Article; Research Support, Non-U.S. Gov't
Journal Info: Publisher: Elsevier Country of Publication: United States NLM ID: 8801383 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1878-5921 (Electronic) Linking ISSN: 08954356 NLM ISO Abbreviation: J Clin Epidemiol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Christensen+R%22">Christensen R</searchLink>; Section for Biostatistics and Evidence-Based Research, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark; Department of Clinical Research, Center of Rheumatic Research Odense (CERRO), University of Southern Denmark, Odense University Hospital, Odense, Denmark; Department of Clinical Research, Cochrane Denmark & Centre for Evidence-Based Medicine Odense (CEBMO), University of Southern Denmark, Odense, Denmark.<br /><searchLink fieldCode="AU" term="%22Berthelsen+DB%22">Berthelsen DB</searchLink>; Section for Biostatistics and Evidence-Based Research, The Parker Institute, Bispebjerg and Frederiksberg Hospital, Copenhagen, Denmark; Department of Clinical Research, Center of Rheumatic Research Odense (CERRO), University of Southern Denmark, Odense University Hospital, Odense, Denmark; Department of Rehabilitation, Municipality of Guldborgsund, Nykoebing F, Denmark. Electronic address: dorthe.bang.berthelsen@regionh.dk.<br /><searchLink fieldCode="AU" term="%22Tugwell+P%22">Tugwell P</searchLink>; Department of Medicine and School of Epidemiology and Public Health Bruyere Research Institute, Ottawa Hospital Research Institute, University of Ottawa, Ottawa, Canada.<br /><searchLink fieldCode="AU" term="%22Golder+S%22">Golder S</searchLink>; Department of Health Sciences, University of York, Heslington, UK.<br /><searchLink fieldCode="AU" term="%22Qureshi+R%22">Qureshi R</searchLink>; Department of Ophthalmology, School of Medicine, University of Colorado Anschutz Medical Campus, Aurora, CO, USA.<br /><searchLink fieldCode="AU" term="%22Mayo-Wilson+E%22">Mayo-Wilson E</searchLink>; Department of Epidemiology, UNC Gillings School of Global Public Health, Chapel Hill, NC, 27599, USA.<br /><searchLink fieldCode="AU" term="%22Simon+LS%22">Simon LS</searchLink>; SDG LLC Cambridge, MA, 02138, USA.<br /><searchLink fieldCode="AU" term="%22Kwong+J%22">Kwong J</searchLink>; Global Health Nursing, Graduate School of Nursing Science, St Luke's International University, Tokyo, Japan.<br /><searchLink fieldCode="AU" term="%22Williamson+PR%22">Williamson PR</searchLink>; Department of Health Data Science, Medical Research Council-National Institute for Health and Care Research Trials Methodology Research Partnership, University of Liverpool, Liverpool, UK.<br /><searchLink fieldCode="AU" term="%22Vohra+S%22">Vohra S</searchLink>; Departments of Pediatrics and Psychiatry, Faculty of Medicine & Dentistry, University of Alberta, Edmonton, Alberta, Canada.
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  Data: <searchLink fieldCode="JN" term="%228801383%22">Journal of clinical epidemiology</searchLink> [J Clin Epidemiol] 2026 Jun; Vol. 194, pp. 112218. <i>Date of Electronic Publication: </i>2026 Mar 07.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%22">Elsevier </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>8801383 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1878-5921 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2208954356%22">08954356 </searchLink><i>NLM ISO Abbreviation: </i>J Clin Epidemiol <i>Subsets: </i>MEDLINE
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              Text: 2026 Jun
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