Cereblon (CRBN) inhibits prostate cancer metastasis by negatively regulating 6-phosphogluconate dehydrogenase (6PGD).

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Title: Cereblon (CRBN) inhibits prostate cancer metastasis by negatively regulating 6-phosphogluconate dehydrogenase (6PGD).
Authors: Guchhait K; Department of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Yoon HS; Department of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., An HS; Department of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Shin S; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Nam HS; Department of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Yanqui-Rivera FD; Department of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Oña SM; Instituto de Simulación Computacional (ISC-USFQ), Universidad San Francisco de Quito, Quito, Ecuador., Mendez MÁ; Instituto de Simulación Computacional (ISC-USFQ), Universidad San Francisco de Quito, Quito, Ecuador.; Colegio de Ciencias e Ingenierías, Politécnico, Universidad San Francisco de Quito, Quito, Ecuador., Hwang JY; Therapeutics & Biotechnology Division, Korea Research Institute of Chemical Technology (KRICT), Daejeon, Korea., Park D; Department of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Park CS; Department of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea., Han JY; Department of Pathology, Inha University Hospital, Incheon, Korea., Chung DY; Department of Urology, Inha University Hospital, Incheon, Korea., Park S; Department of Brain and Cognitive Sciences, Neurometabolomics Research Center, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Korea., Kim EK; Department of Brain and Cognitive Sciences, Neurometabolomics Research Center, Daegu Gyeongbuk Institute of Science and Technology (DGIST), Daegu, Korea., Yang SG; Department of Biomedical Science, BK21 FOUR program in Biomedical Science and Engineering, Inha University College of Medicine, Incheon, Korea., Cho SK; Department of Life Sciences, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea. scho@gist.ac.kr.; Department of Biomedical Science and Engineering, Gwangju Institute of Science and Technology (GIST), Gwangju, Korea. scho@gist.ac.kr.; Integrated Institute of Biomedical Research (IIBR), Gwangju Institute of Science and Technology (GIST), Gwangju, Korea. scho@gist.ac.kr.
Source: Oncogene [Oncogene] 2026 Apr; Vol. 45 (14), pp. 1234-1246. Date of Electronic Publication: 2026 Mar 09.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8711562 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1476-5594 (Electronic) Linking ISSN: 09509232 NLM ISO Abbreviation: Oncogene Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1476-5594
DOI:10.1038/s41388-026-03717-9