Structural basis of allosteric activation of Mycobacterium tuberculosis isocitrate lyase 2.
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| Title: | Structural basis of allosteric activation of Mycobacterium tuberculosis isocitrate lyase 2. |
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| Authors: | Huang EY; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.; School of BioSciences, The University of Melbourne, Parkville, VIC, Australia., Kwai BXC; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia. brooke.kwai@monash.edu.; School of Chemical Sciences, The University of Auckland, Auckland, New Zealand. brooke.kwai@monash.edu.; Monash Institute of Pharmaceutical Sciences, Monash University, Parkville, VIC, Australia. brooke.kwai@monash.edu., Jiao W; Ferrier Research Institute, Victoria University of Wellington, Wellington, New Zealand.; Maurice Wilkins Centre for Molecular Biodiscovery, The University of Auckland, Auckland, New Zealand., Taka J; Laboratory of Microbial Biochemistry and Biotechnology, School of Biological Sciences, The University of Auckland, Auckland, New Zealand., Wilde KL; National Deuteration Facility, Australian Nuclear Science and Technology Organisation, Lucas Heights, NSW, Australia., Sethi A; The Australian Synchrotron, Australian Nuclear Science Technology Organisation, Clayton, VIC, Australia., Maher MJ; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia.; Department of Biochemistry and Pharmacology, The University of Melbourne, Parkville, VIC, Australia., Bashiri G; Laboratory of Microbial Biochemistry and Biotechnology, School of Biological Sciences, The University of Auckland, Auckland, New Zealand., Leung IKH; School of Chemistry and Bio21 Molecular Science and Biotechnology Institute, The University of Melbourne, Parkville, VIC, Australia. ivanhoe.leung@unimelb.edu.au.; School of Chemical Sciences, The University of Auckland, Auckland, New Zealand. ivanhoe.leung@unimelb.edu.au. |
| Source: | Communications biology [Commun Biol] 2026 Mar 09; Vol. 9 (1). Date of Electronic Publication: 2026 Mar 09. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group UK Country of Publication: England NLM ID: 101719179 Publication Model: Electronic Cited Medium: Internet ISSN: 2399-3642 (Electronic) Linking ISSN: 23993642 NLM ISO Abbreviation: Commun Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2399-3642 |
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| DOI: | 10.1038/s42003-026-09821-6 |
