Altered trafficking of Kv1-Kvβ2 leads to neuronal hyperexcitability and memory deficits in amyloid-β pathology.

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Title: Altered trafficking of Kv1-Kvβ2 leads to neuronal hyperexcitability and memory deficits in amyloid-β pathology.
Authors: Cho YS; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea., Kim SH; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea.; Department of Neurology, Institute for Cell Engineering, Johns Hopkins University School of Medicine, Baltimore, MD, 21205, USA., Ryu SH; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea., Chung C; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, 03080, Korea., Lee N; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea., Kim N; Interdisciplinary Program in Neuroscience, Seoul National University, Seoul, 08826, Korea., Jeong M; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea., Kim Y; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea., Gwak J; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea., Choi SY; Department of Physiology, Dental Research Institute, Seoul National University School of Dentistry, Seoul, 03080, Korea., Saido T; Laboratory for Proteolytic Neuroscience, RIKEN Center for Brain Science, Saitama, 3510198, Japan., Jung YK; School of Biological Sciences, Seoul National University, 1 Gwanak-ro, Gwanak-gu, Seoul, 08826, Republic of Korea. ykjung@snu.ac.kr.; Interdisciplinary Program in Neuroscience, Seoul National University, Seoul, 08826, Korea. ykjung@snu.ac.kr.
Source: Molecular neurodegeneration [Mol Neurodegener] 2026 Mar 10; Vol. 21 (1). Date of Electronic Publication: 2026 Mar 10.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101266600 Publication Model: Electronic Cited Medium: Internet ISSN: 1750-1326 (Electronic) Linking ISSN: 17501326 NLM ISO Abbreviation: Mol Neurodegener Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1750-1326
DOI:10.1186/s13024-026-00936-2