Repurposing a detrimental antibody epitope as targeted therapeutics for sepsis and rheumatoid arthritis.

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Title: Repurposing a detrimental antibody epitope as targeted therapeutics for sepsis and rheumatoid arthritis.
Authors: Chen WQ; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030 USA.; Departments of Emergency Medicine and/Or Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549 USA., Lou L; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030 USA., Qiang XL; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030 USA.; Departments of Emergency Medicine and/Or Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549 USA., Zhu CS; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030 USA.; Departments of Emergency Medicine and/Or Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549 USA., Li JH; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030 USA., Chen SJ; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030 USA., Xiong B; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030 USA., Yang H; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030 USA., Wang P; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030 USA.; Departments of Emergency Medicine and/Or Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549 USA., Tracey KJ; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030 USA.; Departments of Emergency Medicine and/Or Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549 USA., Wang HC; The Feinstein Institutes for Medical Research, Northwell Health, Manhasset, NY 11030 USA.; Departments of Emergency Medicine and/Or Molecular Medicine, Donald and Barbara Zucker School of Medicine at Hofstra/Northwell, Hempstead, NY 11549 USA.
Source: Military Medical Research [Mil Med Res] 2026 Feb 17; Vol. 12, pp. 98. Date of Electronic Publication: 2026 Feb 17 (Print Publication: 2025).
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101643181 Publication Model: eCollection Cited Medium: Internet ISSN: 2054-9369 (Electronic) Linking ISSN: 20549369 NLM ISO Abbreviation: Mil Med Res Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2054-9369
DOI:10.1186/s40779-026-00686-8