m6A reader Ythdf proteins control retrotransposon B2 repeat expression and safeguard early embryo development.
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| Title: | m6A reader Ythdf proteins control retrotransposon B2 repeat expression and safeguard early embryo development. |
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| Authors: | Su R; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China. surb@gd2h.org.cn., Gao D; Department of Obstetrics and Gynecology, Reproductive Medicine Center, The First Affiliated Hospital of Bengbu Medical University, 233004, Bengbu, China., Du Z; School of Artificial Intelligence, University of Chinese Academy of Sciences, 100049, Beijing, China., Meng TG; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Li C; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Chen LN; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Lin X; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Cao C; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 100037, Beijing, China., Fan LH; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Dong Y; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China., Li S; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China., Luo SM; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Jiang S; Henan Academy of Innovations in Medical Science, 451163, Zhengzhou, China., Guo Z; Center for Biological Science and Technology, Advanced Institute of Natural Sciences, Beijing Normal University, 519087, Zhuhai, China., Tian Y; Shaanxi Key Laboratory of Earth Surface System and Environmental Carrying Capacity, College of Urban and Environmental Sciences, Northwest University, 710127, Xi'an, China., Sun QY; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China. sunqy@gd2h.org.cn.; Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, 510632, Guangzhou, China. sunqy@gd2h.org.cn.; Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, 510515, Guangzhou, China. sunqy@gd2h.org.cn., Ou XH; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China. ouxh@gd2h.org.cn. |
| Source: | The EMBO journal [EMBO J] 2026 Apr; Vol. 45 (8), pp. 2494-2522. Date of Electronic Publication: 2026 Mar 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1460-2075 |
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| DOI: | 10.1038/s44318-026-00728-w |
