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m6A reader Ythdf proteins control retrotransposon B2 repeat expression and safeguard early embryo development.

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Title: m6A reader Ythdf proteins control retrotransposon B2 repeat expression and safeguard early embryo development.
Authors: Su R; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China. surb@gd2h.org.cn., Gao D; Department of Obstetrics and Gynecology, Reproductive Medicine Center, The First Affiliated Hospital of Bengbu Medical University, 233004, Bengbu, China., Du Z; School of Artificial Intelligence, University of Chinese Academy of Sciences, 100049, Beijing, China., Meng TG; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Li C; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Chen LN; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Lin X; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Cao C; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 100037, Beijing, China., Fan LH; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Dong Y; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China., Li S; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China., Luo SM; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China., Jiang S; Henan Academy of Innovations in Medical Science, 451163, Zhengzhou, China., Guo Z; Center for Biological Science and Technology, Advanced Institute of Natural Sciences, Beijing Normal University, 519087, Zhuhai, China., Tian Y; Shaanxi Key Laboratory of Earth Surface System and Environmental Carrying Capacity, College of Urban and Environmental Sciences, Northwest University, 710127, Xi'an, China., Sun QY; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China. sunqy@gd2h.org.cn.; Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, 510632, Guangzhou, China. sunqy@gd2h.org.cn.; Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, 510515, Guangzhou, China. sunqy@gd2h.org.cn., Ou XH; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China. ouxh@gd2h.org.cn.
Source: The EMBO journal [EMBO J] 2026 Apr; Vol. 45 (8), pp. 2494-2522. Date of Electronic Publication: 2026 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: England NLM ID: 8208664 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1460-2075 (Electronic) Linking ISSN: 02614189 NLM ISO Abbreviation: EMBO J Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: m<superscript>6</superscript>A reader Ythdf proteins control retrotransposon B2 repeat expression and safeguard early embryo development.
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  Data: <searchLink fieldCode="AU" term="%22Su+R%22">Su R</searchLink>; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China. surb@gd2h.org.cn.<br /><searchLink fieldCode="AU" term="%22Gao+D%22">Gao D</searchLink>; Department of Obstetrics and Gynecology, Reproductive Medicine Center, The First Affiliated Hospital of Bengbu Medical University, 233004, Bengbu, China.<br /><searchLink fieldCode="AU" term="%22Du+Z%22">Du Z</searchLink>; School of Artificial Intelligence, University of Chinese Academy of Sciences, 100049, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Meng+TG%22">Meng TG</searchLink>; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Li+C%22">Li C</searchLink>; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Chen+LN%22">Chen LN</searchLink>; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Lin+X%22">Lin X</searchLink>; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Cao+C%22">Cao C</searchLink>; State Key Laboratory of Cardiovascular Disease, Fuwai Hospital, National Center for Cardiovascular Diseases, Chinese Academy of Medical Sciences and Peking Union Medical College, 100037, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Fan+LH%22">Fan LH</searchLink>; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Dong+Y%22">Dong Y</searchLink>; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Li+S%22">Li S</searchLink>; Key Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, 100101, Beijing, China.<br /><searchLink fieldCode="AU" term="%22Luo+SM%22">Luo SM</searchLink>; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China.<br /><searchLink fieldCode="AU" term="%22Jiang+S%22">Jiang S</searchLink>; Henan Academy of Innovations in Medical Science, 451163, Zhengzhou, China.<br /><searchLink fieldCode="AU" term="%22Guo+Z%22">Guo Z</searchLink>; Center for Biological Science and Technology, Advanced Institute of Natural Sciences, Beijing Normal University, 519087, Zhuhai, China.<br /><searchLink fieldCode="AU" term="%22Tian+Y%22">Tian Y</searchLink>; Shaanxi Key Laboratory of Earth Surface System and Environmental Carrying Capacity, College of Urban and Environmental Sciences, Northwest University, 710127, Xi'an, China.<br /><searchLink fieldCode="AU" term="%22Sun+QY%22">Sun QY</searchLink>; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China. sunqy@gd2h.org.cn.; Key Laboratory of Regenerative Medicine of Ministry of Education, Jinan University, 510632, Guangzhou, China. sunqy@gd2h.org.cn.; Department of Developmental Biology, School of Basic Medical Sciences, Southern Medical University, 510515, Guangzhou, China. sunqy@gd2h.org.cn.<br /><searchLink fieldCode="AU" term="%22Ou+XH%22">Ou XH</searchLink>; Guangzhou Key Laboratory of Metabolic Diseases and Reproductive Health, Guangdong-Hong Kong Metabolism & Reproduction Joint Laboratory, Reproductive Medicine Center, the Affiliated Guangdong Second Provincial General Hospital of Jinan University, 510317, Guangzhou, China. ouxh@gd2h.org.cn.
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  Data: <searchLink fieldCode="JN" term="%228208664%22">The EMBO journal</searchLink> [EMBO J] 2026 Apr; Vol. 45 (8), pp. 2494-2522. <i>Date of Electronic Publication: </i>2026 Mar 11.
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        Value: 10.1038/s44318-026-00728-w
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        Text: English
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