Structure-function relationship of alpha-synuclein fibrillar polymorphs derived from distinct synucleinopathies.
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| Title: | Structure-function relationship of alpha-synuclein fibrillar polymorphs derived from distinct synucleinopathies. |
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| Authors: | Serdiuk T; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland., Redeker V; Institut Francois Jacob (MIRCen), CEA, and Laboratory of Neurodegenerative Diseases, CNRS, Université Paris-Saclay, Fontenay-Aux-Roses, France., Savistchenko J; Institut Francois Jacob (MIRCen), CEA, and Laboratory of Neurodegenerative Diseases, CNRS, Université Paris-Saclay, Fontenay-Aux-Roses, France., Neupane S; Institute of Neuropathology, University of Zurich, Zurich, Switzerland., Haenseler W; URPP Adaptive Brain Circuits in Development and Learning, University of Zurich, Zurich, Switzerland., Fleischmann Y; Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland., Reber V; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland., Keller S; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland., Tiberi C; Biozentrum, University of Basel, Basel, Switzerland., Bachmann-Gagescu R; URPP Adaptive Brain Circuits in Development and Learning, University of Zurich, Zurich, Switzerland.; Department of Molecular Life Sciences, University of Zurich, Zurich, Switzerland.; Institute of Medical Genetics, University of Zurich, Schlieren, Zürich, Switzerland., Gstaiger M; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland., Braun T; Biozentrum, University of Basel, Basel, Switzerland., Riek R; Laboratory of Physical Chemistry, ETH Zurich, Zurich, Switzerland., Gentleman S; Department of Brain Sciences, Hammersmith Hospital, Imperial College London, London, UK., Aguzzi A; Institute of Neuropathology, University of Zurich, Zurich, Switzerland., de Souza N; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland., Melki R; Institut Francois Jacob (MIRCen), CEA, and Laboratory of Neurodegenerative Diseases, CNRS, Université Paris-Saclay, Fontenay-Aux-Roses, France. ronald.melki@cnrs.fr., Picotti P; Institute of Molecular Systems Biology, Department of Biology, ETH Zurich, Zurich, Switzerland. picotti@imsb.biol.ethz.ch. |
| Source: | Molecular systems biology [Mol Syst Biol] 2026 Jun; Vol. 22 (6), pp. 868-901. Date of Electronic Publication: 2026 Mar 11. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: EMBO Press Country of Publication: Germany NLM ID: 101235389 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1744-4292 (Electronic) Linking ISSN: 17444292 NLM ISO Abbreviation: Mol Syst Biol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1744-4292 |
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| DOI: | 10.1038/s44320-026-00199-5 |
