Effects of chemogenetic inhibition of serotonergic raphe-striatal neurons on L-DOPA-induced behaviors and neurochemistry in a rat model of Parkinson's disease.

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Title: Effects of chemogenetic inhibition of serotonergic raphe-striatal neurons on L-DOPA-induced behaviors and neurochemistry in a rat model of Parkinson's disease.
Authors: Budrow CN; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, Binghamton, NY, 13902, USA., Bernal-Conde LD; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ, 85013, USA., Sandoval IM; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ, 85013, USA., Galfano A; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, Binghamton, NY, 13902, USA., Grezenko H; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ, 85013, USA., Velazquez A; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ, 85013, USA., Marmion DJ; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ, 85013, USA., Flores-Barrera E; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA., Venkatesh S; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, Binghamton, NY, 13902, USA., Coyle M; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, Binghamton, NY, 13902, USA., Meyers K; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ, 85013, USA., Nguyen K; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ, 85013, USA., Holden H; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, Binghamton, NY, 13902, USA., Tseng KY; Department of Anatomy and Cell Biology, College of Medicine, University of Illinois at Chicago, Chicago, IL, 60612, USA., Bishop CR; Behavioral Neuroscience Program, Department of Psychology, Binghamton University, Binghamton, NY, 13902, USA. cbishop@binghamton.edu., Manfredsson FP; Department of Translational Neuroscience, Barrow Neurological Institute, Phoenix, AZ, 85013, USA. Fredric.manfredsson@barrowneuro.org.
Source: Acta neuropathologica communications [Acta Neuropathol Commun] 2026 Mar 11; Vol. 14 (1). Date of Electronic Publication: 2026 Mar 11.
Publication Type: Journal Article
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101610673 Publication Model: Electronic Cited Medium: Internet ISSN: 2051-5960 (Electronic) Linking ISSN: 20515960 NLM ISO Abbreviation: Acta Neuropathol Commun Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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ISSN:2051-5960
DOI:10.1186/s40478-026-02221-1