Suppression of In Vitro Epileptiform Activity by GABA Transaminase Inhibition Is Dependent on GABAB Receptors and GABA Transporter Type 1 (GAT1).

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Title: Suppression of In Vitro Epileptiform Activity by GABA Transaminase Inhibition Is Dependent on GABAB Receptors and GABA Transporter Type 1 (GAT1).
Authors: Holmes-Léon G; Epilepsy Center of Excellence, VA Puget Sound, Seattle, Washington 98108.; Departments of Neurology, University of Washington, Seattle, Washington., Li N; Epilepsy Center of Excellence, VA Puget Sound, Seattle, Washington 98108.; Departments of Neurology, University of Washington, Seattle, Washington., Albrecht J; Epilepsy Center of Excellence, VA Puget Sound, Seattle, Washington 98108.; Departments of Neurology, University of Washington, Seattle, Washington., Newkirk GS; Epilepsy Center of Excellence, VA Puget Sound, Seattle, Washington 98108.; Departments of Neurology, University of Washington, Seattle, Washington., Nolan A; Epilepsy Center of Excellence, VA Puget Sound, Seattle, Washington 98108.; Pathology and Laboratory Medicine, University of Washington, Seattle, Washington., Ransom CB; Epilepsy Center of Excellence, VA Puget Sound, Seattle, Washington 98108 cbr5@uw.edu.; Departments of Neurology, University of Washington, Seattle, Washington.; Neurobiology and Biophysics, University of Washington, Seattle, Washington.
Source: The Journal of neuroscience : the official journal of the Society for Neuroscience [J Neurosci] 2026 Apr 15; Vol. 46 (15). Date of Electronic Publication: 2026 Apr 15.
Publication Type: Journal Article
Journal Info: Publisher: Society for Neuroscience Country of Publication: United States NLM ID: 8102140 Publication Model: Electronic Cited Medium: Internet ISSN: 1529-2401 (Electronic) Linking ISSN: 02706474 NLM ISO Abbreviation: J Neurosci Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1529-2401
DOI:10.1523/JNEUROSCI.1075-25.2026