View in EDS HTML Full Text PDF Full Text

PARK19 truncation mutant Dnajc6 causes lysosomal deficiency-induced upregulation of pathologic α-synuclein and neurodegeneration of substantia nigra dopaminergic cells in PARK19 knockin mice.

Saved in:
Bibliographic Details
Title: PARK19 truncation mutant Dnajc6 causes lysosomal deficiency-induced upregulation of pathologic α-synuclein and neurodegeneration of substantia nigra dopaminergic cells in PARK19 knockin mice.
Authors: Wang HL; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Healthy Aging Research Center, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan., Chen YL; Department of Nursing, Chang Gung University of Science and Technology, Taoyuan, Taiwan., Chiu TJ; Graduate Institute of Biomedical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan., Chiu CC; Healthy Aging Research Center, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Medical Biotechnology and Laboratory Science, Chang Gung University College of Medicine, Taoyuan, Taiwan., Weng YH; Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan., Liu SY; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan., Li AH; Department of Anesthesiology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan., Yeh TH; Department of Neurology, Taipei Medical University Hospital, Taipei, Taiwan. do2739@tmu.edu.tw.; School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. do2739@tmu.edu.tw.; Taipei Neuroscience Institute, Taipei Medical University, Taipei, Taiwan. do2739@tmu.edu.tw.
Source: NPJ Parkinson's disease [NPJ Parkinsons Dis] 2026 Mar 12; Vol. 12 (1). Date of Electronic Publication: 2026 Mar 12.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101675390 Publication Model: Electronic Cited Medium: Print ISSN: 2373-8057 (Print) Linking ISSN: 23738057 NLM ISO Abbreviation: NPJ Parkinsons Dis Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Full text is not displayed to guests.
FullText Links:
  – Type: pdflink
Text:
  Availability: 1
Header DbId: mdl
DbLabel: MEDLINE Ultimate
An: 41820376
AccessLevel: 2
PubType: Academic Journal
PubTypeId: academicJournal
PreciseRelevancyScore: 0
IllustrationInfo
Items – Name: Title
  Label: Title
  Group: Ti
  Data: PARK19 truncation mutant Dnajc6 causes lysosomal deficiency-induced upregulation of pathologic α-synuclein and neurodegeneration of substantia nigra dopaminergic cells in PARK19 knockin mice.
– Name: Author
  Label: Authors
  Group: Au
  Data: <searchLink fieldCode="AU" term="%22Wang+HL%22">Wang HL</searchLink>; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Healthy Aging Research Center, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chen+YL%22">Chen YL</searchLink>; Department of Nursing, Chang Gung University of Science and Technology, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiu+TJ%22">Chiu TJ</searchLink>; Graduate Institute of Biomedical Sciences, Chang Gung University College of Medicine, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Chiu+CC%22">Chiu CC</searchLink>; Healthy Aging Research Center, Chang Gung University College of Medicine, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Department of Medical Biotechnology and Laboratory Science, Chang Gung University College of Medicine, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Weng+YH%22">Weng YH</searchLink>; Division of Movement Disorders, Department of Neurology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; Neuroscience Research Center, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.; College of Medicine, Chang Gung University, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Liu+SY%22">Liu SY</searchLink>; Department of Physiology and Pharmacology, Chang Gung University College of Medicine, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Li+AH%22">Li AH</searchLink>; Department of Anesthesiology, Chang Gung Memorial Hospital at Linkou, Taoyuan, Taiwan.<br /><searchLink fieldCode="AU" term="%22Yeh+TH%22">Yeh TH</searchLink>; Department of Neurology, Taipei Medical University Hospital, Taipei, Taiwan. do2739@tmu.edu.tw.; School of Medicine, College of Medicine, Taipei Medical University, Taipei, Taiwan. do2739@tmu.edu.tw.; Taipei Neuroscience Institute, Taipei Medical University, Taipei, Taiwan. do2739@tmu.edu.tw.
– Name: TitleSource
  Label: Source
  Group: Src
  Data: <searchLink fieldCode="JN" term="%22101675390%22">NPJ Parkinson's disease</searchLink> [NPJ Parkinsons Dis] 2026 Mar 12; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Mar 12.
– Name: TypePub
  Label: Publication Type
  Group: TypPub
  Data: Journal Article
– Name: TitleSource
  Label: Journal Info
  Group: Src
  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101675390 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2373-8057 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2223738057%22">23738057 </searchLink><i>NLM ISO Abbreviation: </i>NPJ Parkinsons Dis <i>Subsets: </i>PubMed not MEDLINE
PLink https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41820376
RecordInfo BibRecord:
  BibEntity:
    Identifiers:
      – Type: doi
        Value: 10.1038/s41531-026-01317-8
    Languages:
      – Code: eng
        Text: English
    Titles:
      – TitleFull: PARK19 truncation mutant Dnajc6 causes lysosomal deficiency-induced upregulation of pathologic α-synuclein and neurodegeneration of substantia nigra dopaminergic cells in PARK19 knockin mice.
        Type: main
  BibRelationships:
    HasContributorRelationships:
      – PersonEntity:
          Name:
            NameFull: Wang HL
      – PersonEntity:
          Name:
            NameFull: Chen YL
      – PersonEntity:
          Name:
            NameFull: Chiu TJ
      – PersonEntity:
          Name:
            NameFull: Chiu CC
      – PersonEntity:
          Name:
            NameFull: Weng YH
      – PersonEntity:
          Name:
            NameFull: Liu SY
      – PersonEntity:
          Name:
            NameFull: Li AH
      – PersonEntity:
          Name:
            NameFull: Yeh TH
    IsPartOfRelationships:
      – BibEntity:
          Dates:
            – D: 12
              M: 03
              Text: 2026 Mar 12
              Type: published
              Y: 2026
          Identifiers:
            – Type: issn-print
              Value: 2373-8057
          Numbering:
            – Type: volume
              Value: 12
            – Type: issue
              Value: 1
          Titles:
            – TitleFull: NPJ Parkinson's disease
              Type: main
ResultId 1