Impact of CYP2D6 Metabolizer Status on Ondansetron Efficacy in Early Pregnancy Induced Nausea and Vomiting: A Case Control Study.
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| Title: | Impact of CYP2D6 Metabolizer Status on Ondansetron Efficacy in Early Pregnancy Induced Nausea and Vomiting: A Case Control Study. |
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| Authors: | Liu M; Department of Pharmacy, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Shuey MM; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Holley SE; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Fountain DF; Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Jaworski J; Division of Epidemiology, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Griffin C; School of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Kim J; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Vanderbilt Genetics Institute, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; School of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Division of Quantitative and Clinical Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Stec M; School of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Sunthankar SD; Department of Pediatrics, Pediatric Cardiology and Center for Pediatric Precision Medicine, Monroe Carell Jr. Children's Hospital at Vanderbilt, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Ong HH; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Gangireddy S; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Wei WQ; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Gaedigk A; Division of Clinical Pharmacology, Toxicology & Therapeutic Innovation, Children's Mercy Research Institute, Kansas City, Missouri, USA.; School of Medicine, University of Missouri-Kansas City, Kansas City, Missouri, USA., Velez Edwards DR; Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Division of Quantitative and Clinical Sciences, Department of Obstetrics and Gynecology, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Biomedical Informatics, Vanderbilt University Medical Center, Nashville, Tennessee, USA., Kawai VK; Division of Genetic Medicine, Department of Medicine, Vanderbilt University Medical Center, Nashville, Tennessee, USA.; Department of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, USA. |
| Source: | Clinical and translational science [Clin Transl Sci] 2026 Mar; Vol. 19 (3), pp. e70523. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: WileyBlackwell Pub Country of Publication: United States NLM ID: 101474067 Publication Model: Print Cited Medium: Internet ISSN: 1752-8062 (Electronic) Linking ISSN: 17528054 NLM ISO Abbreviation: Clin Transl Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1752-8062 |
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| DOI: | 10.1111/cts.70523 |