Early rise in nasal secretory IgA associated with shorter duration of SARS-CoV-2 virus shedding in an acute infection cohort.

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Title: Early rise in nasal secretory IgA associated with shorter duration of SARS-CoV-2 virus shedding in an acute infection cohort.
Authors: Brackett C; Departments of Surgery and Integrative Immunobiology, Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States., Zhang L; Departments of Surgery and Integrative Immunobiology, Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States., Do BTN; Departments of Surgery and Integrative Immunobiology, Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States., Baral S; Departments of Surgery and Integrative Immunobiology, Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States., Fisher LH; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States., Hahn WO; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States., Carnacchi AJ; Departments of Surgery and Integrative Immunobiology, Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States., Hilliard S; Departments of Surgery and Integrative Immunobiology, Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States., Li SS; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States., Premkumar L; Department of Microbiology and Immunology, University of North Carolina, Chapel Hill, NC, United States., Greninger AL; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States.; Department of Laboratory Medicine and Pathology, University of Washington Medical Center, Seattle, WA, United States., Hyrien O; Vaccine and Infectious Disease Division, Fred Hutchinson Cancer Research Center, Seattle, WA, United States., Seaton KE; Departments of Surgery and Integrative Immunobiology, Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States., Tomaras GD; Departments of Surgery and Integrative Immunobiology, Center for Human Systems Immunology, Duke University School of Medicine, Durham, NC, United States.
Source: Frontiers in immunology [Front Immunol] 2026 Feb 25; Vol. 17, pp. 1722585. Date of Electronic Publication: 2026 Feb 25 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1722585