The dolutegravir failure cohort: A multi-country longitudinal cohort with a randomised clinical trial of continued dolutegravir versus switch to darunavir in people with viraemia while on dolutegravir in Sub-Saharan Africa (The Ndovu Study) protocol.
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| Title: | The dolutegravir failure cohort: A multi-country longitudinal cohort with a randomised clinical trial of continued dolutegravir versus switch to darunavir in people with viraemia while on dolutegravir in Sub-Saharan Africa (The Ndovu Study) protocol. |
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| Authors: | Ombajo LA; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya., Nkuranga J; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya., Penner J; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya.; Department of Family Practice, University of British Columbia, Vancouver, Canada., Kamau EW; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya., Ismael N; Instituto Nacional de Saúde, Marracuene, Mozambique., Munseri P; Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania., Ayakaka I; SolidarMed - Partnerships for Health, Maseru, Lesotho., Labhardt N; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland., Wamalwa D; Department of Paediatrics, University of Nairobi, Nairobi, Kenya., Ramgi P; Instituto Nacional de Saúde, Marracuene, Mozambique., Chissumba RM; Instituto Nacional de Saúde, Marracuene, Mozambique.; Centro de Investigação e Desenvolvimento em Etnobotânica, Namaacha, Mozambique., Wagude J; Siaya County Referral Hospital, Siaya, Kenya., Bakari M; Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania., Omodi V; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya., Otieno E; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya., Abuogi L; Department of Pediatrics, University of Colorado, Aurora, Colorado, United States of America., Patel R; Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Opondo C; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom., Grint D; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom., King'wara L; Kenya National Public Health Institute, Nairobi, Kenya., Macharia A; Department of Paediatrics, Kenyatta National Hospital, Nairobi, Kenya., Mulwa A; National AIDS/STI Control Program, Ministry of Health Kenya, Nairobi, Kenya., Amoth P; Ministry of Health, Nairobi, Kenya. |
| Corporate Authors: | Ndovu study group |
| Source: | PloS one [PLoS One] 2026 Mar 13; Vol. 21 (3), pp. e0330792. Date of Electronic Publication: 2026 Mar 13 (Print Publication: 2026). |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1932-6203 |
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| DOI: | 10.1371/journal.pone.0330792 |
