The dolutegravir failure cohort: A multi-country longitudinal cohort with a randomised clinical trial of continued dolutegravir versus switch to darunavir in people with viraemia while on dolutegravir in Sub-Saharan Africa (The Ndovu Study) protocol.
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| Title: | The dolutegravir failure cohort: A multi-country longitudinal cohort with a randomised clinical trial of continued dolutegravir versus switch to darunavir in people with viraemia while on dolutegravir in Sub-Saharan Africa (The Ndovu Study) protocol. |
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| Authors: | Ombajo LA; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya., Nkuranga J; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya., Penner J; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya.; Department of Family Practice, University of British Columbia, Vancouver, Canada., Kamau EW; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya., Ismael N; Instituto Nacional de Saúde, Marracuene, Mozambique., Munseri P; Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania., Ayakaka I; SolidarMed - Partnerships for Health, Maseru, Lesotho., Labhardt N; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland., Wamalwa D; Department of Paediatrics, University of Nairobi, Nairobi, Kenya., Ramgi P; Instituto Nacional de Saúde, Marracuene, Mozambique., Chissumba RM; Instituto Nacional de Saúde, Marracuene, Mozambique.; Centro de Investigação e Desenvolvimento em Etnobotânica, Namaacha, Mozambique., Wagude J; Siaya County Referral Hospital, Siaya, Kenya., Bakari M; Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania., Omodi V; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya., Otieno E; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya., Abuogi L; Department of Pediatrics, University of Colorado, Aurora, Colorado, United States of America., Patel R; Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America., Opondo C; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom., Grint D; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom., King'wara L; Kenya National Public Health Institute, Nairobi, Kenya., Macharia A; Department of Paediatrics, Kenyatta National Hospital, Nairobi, Kenya., Mulwa A; National AIDS/STI Control Program, Ministry of Health Kenya, Nairobi, Kenya., Amoth P; Ministry of Health, Nairobi, Kenya. |
| Corporate Authors: | Ndovu study group |
| Source: | PloS one [PLoS One] 2026 Mar 13; Vol. 21 (3), pp. e0330792. Date of Electronic Publication: 2026 Mar 13 (Print Publication: 2026). |
| Publication Type: | Journal Article; Randomized Controlled Trial; Multicenter Study |
| Journal Info: | Publisher: Public Library of Science Country of Publication: United States NLM ID: 101285081 Publication Model: eCollection Cited Medium: Internet ISSN: 1932-6203 (Electronic) Linking ISSN: 19326203 NLM ISO Abbreviation: PLoS One Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| Header | DbId: mdl DbLabel: MEDLINE Ultimate An: 41824511 AccessLevel: 2 PubType: Academic Journal PubTypeId: academicJournal PreciseRelevancyScore: 0 |
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| Items | – Name: Title Label: Title Group: Ti Data: The dolutegravir failure cohort: A multi-country longitudinal cohort with a randomised clinical trial of continued dolutegravir versus switch to darunavir in people with viraemia while on dolutegravir in Sub-Saharan Africa (The Ndovu Study) protocol. – Name: Author Label: Authors Group: Au Data: <searchLink fieldCode="AU" term="%22Ombajo+LA%22">Ombajo LA</searchLink>; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Nkuranga+J%22">Nkuranga J</searchLink>; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Penner+J%22">Penner J</searchLink>; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya.; Department of Family Practice, University of British Columbia, Vancouver, Canada.<br /><searchLink fieldCode="AU" term="%22Kamau+EW%22">Kamau EW</searchLink>; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Ismael+N%22">Ismael N</searchLink>; Instituto Nacional de Saúde, Marracuene, Mozambique.<br /><searchLink fieldCode="AU" term="%22Munseri+P%22">Munseri P</searchLink>; Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.<br /><searchLink fieldCode="AU" term="%22Ayakaka+I%22">Ayakaka I</searchLink>; SolidarMed - Partnerships for Health, Maseru, Lesotho.<br /><searchLink fieldCode="AU" term="%22Labhardt+N%22">Labhardt N</searchLink>; Division of Clinical Epidemiology, Department of Clinical Research, University Hospital Basel, Basel, Switzerland.<br /><searchLink fieldCode="AU" term="%22Wamalwa+D%22">Wamalwa D</searchLink>; Department of Paediatrics, University of Nairobi, Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Ramgi+P%22">Ramgi P</searchLink>; Instituto Nacional de Saúde, Marracuene, Mozambique.<br /><searchLink fieldCode="AU" term="%22Chissumba+RM%22">Chissumba RM</searchLink>; Instituto Nacional de Saúde, Marracuene, Mozambique.; Centro de Investigação e Desenvolvimento em Etnobotânica, Namaacha, Mozambique.<br /><searchLink fieldCode="AU" term="%22Wagude+J%22">Wagude J</searchLink>; Siaya County Referral Hospital, Siaya, Kenya.<br /><searchLink fieldCode="AU" term="%22Bakari+M%22">Bakari M</searchLink>; Department of Internal Medicine, Muhimbili University of Health and Allied Sciences, Dar es Salaam, Tanzania.<br /><searchLink fieldCode="AU" term="%22Omodi+V%22">Omodi V</searchLink>; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Otieno+E%22">Otieno E</searchLink>; Department of Clinical Medicine and Therapeutics, University of Nairobi, Nairobi, Kenya.; Center for Epidemiological Modelling and Analysis, University of Nairobi, Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Abuogi+L%22">Abuogi L</searchLink>; Department of Pediatrics, University of Colorado, Aurora, Colorado, United States of America.<br /><searchLink fieldCode="AU" term="%22Patel+R%22">Patel R</searchLink>; Department of Medicine, Heersink School of Medicine, University of Alabama at Birmingham, Birmingham, Alabama, United States of America.<br /><searchLink fieldCode="AU" term="%22Opondo+C%22">Opondo C</searchLink>; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22Grint+D%22">Grint D</searchLink>; Faculty of Epidemiology and Population Health, London School of Hygiene and Tropical Medicine, London, United Kingdom.<br /><searchLink fieldCode="AU" term="%22King'wara+L%22">King'wara L</searchLink>; Kenya National Public Health Institute, Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Macharia+A%22">Macharia A</searchLink>; Department of Paediatrics, Kenyatta National Hospital, Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Mulwa+A%22">Mulwa A</searchLink>; National AIDS/STI Control Program, Ministry of Health Kenya, Nairobi, Kenya.<br /><searchLink fieldCode="AU" term="%22Amoth+P%22">Amoth P</searchLink>; Ministry of Health, Nairobi, Kenya. – Name: AuthorCorporate Label: Corporate Authors Group: Au Data: <searchLink fieldCode="CA" term="%22Ndovu+study+group%22">Ndovu study group</searchLink> – Name: TitleSource Label: Source Group: Src Data: <searchLink fieldCode="JN" term="%22101285081%22">PloS one</searchLink> [PLoS One] 2026 Mar 13; Vol. 21 (3), pp. e0330792. <i>Date of Electronic Publication: </i>2026 Mar 13 (<i>Print Publication: </i>2026). – Name: TypePub Label: Publication Type Group: TypPub Data: Journal Article; Randomized Controlled Trial; Multicenter Study – Name: TitleSource Label: Journal Info Group: Src Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Public+Library+of+Science%22">Public Library of Science </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101285081 <i>Publication Model: </i>eCollection <i>Cited Medium: </i>Internet <i>ISSN: </i>1932-6203 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2219326203%22">19326203 </searchLink><i>NLM ISO Abbreviation: </i>PLoS One <i>Subsets: </i>MEDLINE |
| PLink | https://search.ebscohost.com/login.aspx?direct=true&site=eds-live&db=mdl&AN=41824511 |
| RecordInfo | BibRecord: BibEntity: Identifiers: – Type: doi Value: 10.1371/journal.pone.0330792 Languages: – Code: eng Text: English PhysicalDescription: Pagination: StartPage: e0330792 Titles: – TitleFull: The dolutegravir failure cohort: A multi-country longitudinal cohort with a randomised clinical trial of continued dolutegravir versus switch to darunavir in people with viraemia while on dolutegravir in Sub-Saharan Africa (The Ndovu Study) protocol. Type: main BibRelationships: HasContributorRelationships: – PersonEntity: Name: NameFull: Ombajo LA – PersonEntity: Name: NameFull: Nkuranga J – PersonEntity: Name: NameFull: Penner J – PersonEntity: Name: NameFull: Kamau EW – PersonEntity: Name: NameFull: Ismael N – PersonEntity: Name: NameFull: Munseri P – PersonEntity: Name: NameFull: Ayakaka I – PersonEntity: Name: NameFull: Labhardt N – PersonEntity: Name: NameFull: Wamalwa D – PersonEntity: Name: NameFull: Ramgi P – PersonEntity: Name: NameFull: Chissumba RM – PersonEntity: Name: NameFull: Wagude J – PersonEntity: Name: NameFull: Bakari M – PersonEntity: Name: NameFull: Omodi V – PersonEntity: Name: NameFull: Otieno E – PersonEntity: Name: NameFull: Abuogi L – PersonEntity: Name: NameFull: Patel R – PersonEntity: Name: NameFull: Opondo C – PersonEntity: Name: NameFull: Grint D – PersonEntity: Name: NameFull: King'wara L – PersonEntity: Name: NameFull: Macharia A – PersonEntity: Name: NameFull: Mulwa A – PersonEntity: Name: NameFull: Amoth P IsPartOfRelationships: – BibEntity: Dates: – D: 13 M: 03 Text: 2026 Mar 13 Type: published Y: 2026 Identifiers: – Type: issn-electronic Value: 1932-6203 Numbering: – Type: volume Value: 21 – Type: issue Value: 3 Titles: – TitleFull: PloS one Type: main |
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