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Iterative acylation on mature lasso peptides by widespread acetyltransferases.

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Title: Iterative acylation on mature lasso peptides by widespread acetyltransferases.
Authors: Xiong J; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China.; Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, People's Republic of China., Wu S; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China.; Key Laboratory of Magnetism and Magnetic Functional Materials (Lanzhou University), Ministry of Education, Lanzhou, People's Republic of China.; Electron Microscopy Centre of Lanzhou University, Lanzhou University, Lanzhou, People's Republic of China., Liang ZQ; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China., Fang S; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China., Tao FY; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China., Gong XT; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China., Wu X; Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, People's Republic of China., Wu Q; Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, People's Republic of China., Cui JJ; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China., Gao K; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China., Hoi KK; Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, People's Republic of China., Peng Y; Electron Microscopy Centre of Lanzhou University, Lanzhou University, Lanzhou, People's Republic of China. pengy@lzu.edu.cn.; School of Materials and Energy, Lanzhou University, Lanzhou, People's Republic of China. pengy@lzu.edu.cn., Luo S; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China. luosw@lzu.edu.cn.; Academy of Plateau Science and Sustainability, Qinghai Normal University, Xining, People's Republic of China. luosw@lzu.edu.cn., Lei D; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China. leids@lzu.edu.cn.; Key Laboratory of Magnetism and Magnetic Functional Materials (Lanzhou University), Ministry of Education, Lanzhou, People's Republic of China. leids@lzu.edu.cn.; Electron Microscopy Centre of Lanzhou University, Lanzhou University, Lanzhou, People's Republic of China. leids@lzu.edu.cn.; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou, People's Republic of China. leids@lzu.edu.cn., Dong SH; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China. dongsh@lzu.edu.cn.; Academy of Plateau Science and Sustainability, Qinghai Normal University, Xining, People's Republic of China. dongsh@lzu.edu.cn.
Source: Nature chemical biology [Nat Chem Biol] 2026 Jul; Vol. 22 (7), pp. 1176-1186. Date of Electronic Publication: 2026 Mar 13.
Publication Type: Journal Article
Journal Info: Publisher: Nature Pub. Group Country of Publication: United States NLM ID: 101231976 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1552-4469 (Electronic) Linking ISSN: 15524450 NLM ISO Abbreviation: Nat Chem Biol Subsets: MEDLINE
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  Data: Iterative acylation on mature lasso peptides by widespread acetyltransferases.
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  Data: <searchLink fieldCode="AU" term="%22Xiong+J%22">Xiong J</searchLink>; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China.; Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wu+S%22">Wu S</searchLink>; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China.; Key Laboratory of Magnetism and Magnetic Functional Materials (Lanzhou University), Ministry of Education, Lanzhou, People's Republic of China.; Electron Microscopy Centre of Lanzhou University, Lanzhou University, Lanzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Liang+ZQ%22">Liang ZQ</searchLink>; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Fang+S%22">Fang S</searchLink>; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Tao+FY%22">Tao FY</searchLink>; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Gong+XT%22">Gong XT</searchLink>; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wu+X%22">Wu X</searchLink>; Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Wu+Q%22">Wu Q</searchLink>; Institute of Modern Physics, Chinese Academy of Sciences, Lanzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Cui+JJ%22">Cui JJ</searchLink>; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Gao+K%22">Gao K</searchLink>; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Hoi+KK%22">Hoi KK</searchLink>; Institute of Chemical Biology, Shenzhen Bay Laboratory, Shenzhen, People's Republic of China.<br /><searchLink fieldCode="AU" term="%22Peng+Y%22">Peng Y</searchLink>; Electron Microscopy Centre of Lanzhou University, Lanzhou University, Lanzhou, People's Republic of China. pengy@lzu.edu.cn.; School of Materials and Energy, Lanzhou University, Lanzhou, People's Republic of China. pengy@lzu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Luo+S%22">Luo S</searchLink>; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China. luosw@lzu.edu.cn.; Academy of Plateau Science and Sustainability, Qinghai Normal University, Xining, People's Republic of China. luosw@lzu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Lei+D%22">Lei D</searchLink>; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China. leids@lzu.edu.cn.; Key Laboratory of Magnetism and Magnetic Functional Materials (Lanzhou University), Ministry of Education, Lanzhou, People's Republic of China. leids@lzu.edu.cn.; Electron Microscopy Centre of Lanzhou University, Lanzhou University, Lanzhou, People's Republic of China. leids@lzu.edu.cn.; State Key Laboratory for Animal Disease Control and Prevention, College of Veterinary Medicine, Lanzhou University, Lanzhou, People's Republic of China. leids@lzu.edu.cn.<br /><searchLink fieldCode="AU" term="%22Dong+SH%22">Dong SH</searchLink>; State Key Laboratory of Natural Product Chemistry, College of Chemistry and Chemical Engineering, School of Physical Science and Technology, Lanzhou University, Lanzhou, People's Republic of China. dongsh@lzu.edu.cn.; Academy of Plateau Science and Sustainability, Qinghai Normal University, Xining, People's Republic of China. dongsh@lzu.edu.cn.
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  Data: <searchLink fieldCode="JN" term="%22101231976%22">Nature chemical biology</searchLink> [Nat Chem Biol] 2026 Jul; Vol. 22 (7), pp. 1176-1186. <i>Date of Electronic Publication: </i>2026 Mar 13.
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        Value: 10.1038/s41589-026-02149-6
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