Alexander disease mutations differentially sensitize glial fibrillary acidic protein (GFAP) to posttranslational modifications and network disruption by oxidants.

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Title: Alexander disease mutations differentially sensitize glial fibrillary acidic protein (GFAP) to posttranslational modifications and network disruption by oxidants.
Authors: Goya-Iglesias N; Department of Molecular and Cellular and Biosciences, Centro de Investigaciones Biológicas Margarita Salas, C.S.I.C., Madrid, 28040, Spain., Hägglund P; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark., Martínez-Cenalmor P; Department of Molecular and Cellular and Biosciences, Centro de Investigaciones Biológicas Margarita Salas, C.S.I.C., Madrid, 28040, Spain., Nybo T; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark., Lorentzen LG; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark., Pajares MA; Department of Molecular and Cellular and Biosciences, Centro de Investigaciones Biológicas Margarita Salas, C.S.I.C., Madrid, 28040, Spain., Davies MJ; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark. Electronic address: davies@sund.ku.dk., Pérez-Sala D; Department of Molecular and Cellular and Biosciences, Centro de Investigaciones Biológicas Margarita Salas, C.S.I.C., Madrid, 28040, Spain. Electronic address: dperezsala@cib.csic.es.
Source: Redox biology [Redox Biol] 2026 May; Vol. 92, pp. 104103. Date of Electronic Publication: 2026 Mar 04.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier, B.V Country of Publication: Netherlands NLM ID: 101605639 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2213-2317 (Electronic) Linking ISSN: 22132317 NLM ISO Abbreviation: Redox Biol Subsets: MEDLINE
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  Data: Alexander disease mutations differentially sensitize glial fibrillary acidic protein (GFAP) to posttranslational modifications and network disruption by oxidants.
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  Data: <searchLink fieldCode="AU" term="%22Goya-Iglesias+N%22">Goya-Iglesias N</searchLink>; Department of Molecular and Cellular and Biosciences, Centro de Investigaciones Biológicas Margarita Salas, C.S.I.C., Madrid, 28040, Spain.<br /><searchLink fieldCode="AU" term="%22Hägglund+P%22">Hägglund P</searchLink>; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark.<br /><searchLink fieldCode="AU" term="%22Martínez-Cenalmor+P%22">Martínez-Cenalmor P</searchLink>; Department of Molecular and Cellular and Biosciences, Centro de Investigaciones Biológicas Margarita Salas, C.S.I.C., Madrid, 28040, Spain.<br /><searchLink fieldCode="AU" term="%22Nybo+T%22">Nybo T</searchLink>; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark.<br /><searchLink fieldCode="AU" term="%22Lorentzen+LG%22">Lorentzen LG</searchLink>; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark.<br /><searchLink fieldCode="AU" term="%22Pajares+MA%22">Pajares MA</searchLink>; Department of Molecular and Cellular and Biosciences, Centro de Investigaciones Biológicas Margarita Salas, C.S.I.C., Madrid, 28040, Spain.<br /><searchLink fieldCode="AU" term="%22Davies+MJ%22">Davies MJ</searchLink>; Department of Biomedical Sciences, Panum Institute, University of Copenhagen, Copenhagen, 2200, Denmark. Electronic address: davies@sund.ku.dk.<br /><searchLink fieldCode="AU" term="%22Pérez-Sala+D%22">Pérez-Sala D</searchLink>; Department of Molecular and Cellular and Biosciences, Centro de Investigaciones Biológicas Margarita Salas, C.S.I.C., Madrid, 28040, Spain. Electronic address: dperezsala@cib.csic.es.
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  Data: <searchLink fieldCode="JN" term="%22101605639%22">Redox biology</searchLink> [Redox Biol] 2026 May; Vol. 92, pp. 104103. <i>Date of Electronic Publication: </i>2026 Mar 04.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier%2C+B%2EV%22">Elsevier, B.V </searchLink><i>Country of Publication: </i>Netherlands <i>NLM ID: </i>101605639 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>2213-2317 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2222132317%22">22132317 </searchLink><i>NLM ISO Abbreviation: </i>Redox Biol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.redox.2026.104103
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