IL-31 blockade elevates thymus and activation-regulated chemokine by lifting LAMP3+CD1c+ mature dendritic cells from calcitonin gene-related peptide-calcitonin receptor-like neuroimmune suppression in atopic dermatitis.

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Title: IL-31 blockade elevates thymus and activation-regulated chemokine by lifting LAMP3+CD1c+ mature dendritic cells from calcitonin gene-related peptide-calcitonin receptor-like neuroimmune suppression in atopic dermatitis.
Authors: Honryo A; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Research and Development Department, Ikeda Mohando, Toyama, Japan., Masuda T; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Drug Development Research Laboratories, Maruho, Kyoto, Japan; Department of Drug Discovery for Inflammatory Skin Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan., Nakamizo S; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Alliance Laboratory for Advanced Medical Research, Kyoto University Graduate School of Medicine, Kyoto, Japan., Takafuji T; Drug Development Research Laboratories, Maruho, Kyoto, Japan., Minami F; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan., Yonekura S; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan., Uchibayashi M; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Drug Development Research Laboratories, Maruho, Kyoto, Japan; Department of Drug Discovery for Inflammatory Skin Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan., Inoue K; Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Hyogo, Japan., Kiyonari H; Laboratory for Animal Resources and Genetic Engineering, RIKEN Center for Biosystems Dynamics Research, Hyogo, Japan., Yamanaka M; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan., Irie H; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan., Nakashima C; Department of Dermatology, Faculty of Medicine, Kindai University, Osaka, Japan., Nakajima S; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Department of Drug Discovery for Inflammatory Skin Diseases, Kyoto University Graduate School of Medicine, Kyoto, Japan., Otsuka A; Department of Dermatology, Faculty of Medicine, Kindai University, Osaka, Japan. Electronic address: otsukaman@med.kindai.ac.jp., Asahina R; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; Center for One Medicine Innovative Translational Research (COMIT), Institute for Advanced Study, Gifu University, Gifu, Japan. Electronic address: asahina.ryota.r6@f.gifu-u.ac.jp., Kabashima K; Department of Dermatology, Kyoto University Graduate School of Medicine, Kyoto, Japan; A∗STAR Skin Research Labs (A∗SRL), Singapore Immunology Network (SIgN), and Skin Research Institute of Singapore (SRIS), Agency for Science, Technology, and Research (A∗STAR), Singapore. Electronic address: kaba@kuhp.kyoto-u.ac.jp.
Source: The Journal of allergy and clinical immunology [J Allergy Clin Immunol] 2026 Mar 12. Date of Electronic Publication: 2026 Mar 12.
Publication Type: Journal Article
Journal Info: Publisher: Mosby Country of Publication: United States NLM ID: 1275002 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1097-6825 (Electronic) Linking ISSN: 00916749 NLM ISO Abbreviation: J Allergy Clin Immunol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1097-6825
DOI:10.1016/j.jaci.2026.02.044