Weight Regain Reverses Caloric Restriction-Induced Benefits on the Insulin-IGF-1 Nutrient-Sensing Pathway: Post Hoc Analysis From the CALERIE-2 Randomized Controlled Trial.
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| Title: | Weight Regain Reverses Caloric Restriction-Induced Benefits on the Insulin-IGF-1 Nutrient-Sensing Pathway: Post Hoc Analysis From the CALERIE-2 Randomized Controlled Trial. |
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| Authors: | Warmbrunn MV; Charles Perkins Center, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; Department of Internal and Vascular Medicine, Amsterdam University Medical Centers, Amsterdam, the Netherlands., Yang L; Department of Cancer Epidemiology and Prevention Research, Cancer Care Alberta, Alberta Health Services, Calgary, Alberta, Canada.; Departments of Oncology and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada., Kishore Biswas R; Charles Perkins Center, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; Sydney Local Health District Clinical Research Centre, Royal Prince Alfred Hospital, Camperdown, New South Wales, Australia., Ryan CP; Robert N. Butler Columbia Aging Center, Mailman School of Public Health, Columbia University, New York, NY., Harper A; Departments of Oncology and Community Health Sciences, University of Calgary, Calgary, Alberta, Canada., Belsky DW; Robert N. Butler Columbia Aging Center, Mailman School of Public Health, Columbia University, New York, NY.; Department of Epidemiology, Mailman School of Public Health, Columbia University, New York, NY., Fiorito G; Clinical Bioinformatics Unit, IRCCS Istituto Giannina Gaslini, Genoa, Italy.; MRC-PHE Centre for Environment and Health, Imperial College London, London, U.K., Fontana L; Charles Perkins Center, Faculty of Medicine and Health, University of Sydney, Sydney, New South Wales, Australia.; Department of Endocrinology, Royal Prince Alfred Hospital, Sydney, New South Wales, Australia. |
| Source: | Diabetes care [Diabetes Care] 2026 May 01; Vol. 49 (5), pp. 783-791. |
| Publication Type: | Journal Article; Randomized Controlled Trial |
| Journal Info: | Publisher: American Diabetes Association Country of Publication: United States NLM ID: 7805975 Publication Model: Print Cited Medium: Internet ISSN: 1935-5548 (Electronic) Linking ISSN: 01495992 NLM ISO Abbreviation: Diabetes Care Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1935-5548 |
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| DOI: | 10.2337/dc25-1911 |
