A biosafe mouse model for SARS-CoV-2 infection that more realistically simulates COVID-19 symptoms.
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| Title: | A biosafe mouse model for SARS-CoV-2 infection that more realistically simulates COVID-19 symptoms. |
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| Authors: | Huang X; State Key Laboratory of Virology and Biosafety, RNA Institute, College of Life Sciences and Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China., Li Y; State Key Laboratory of Virology and Biosafety, RNA Institute, College of Life Sciences and Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China.; Institute for Vaccine Research at Animal Biosafety Level 3 Laboratory, Wuhan University School of Medicine, Wuhan, China., Deng J; State Key Laboratory of Virology and Biosafety, RNA Institute, College of Life Sciences and Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China., Tan X; State Key Laboratory of Virology and Biosafety, RNA Institute, College of Life Sciences and Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China., Yang S; State Key Laboratory of Virology and Biosafety, RNA Institute, College of Life Sciences and Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China., Liu J; State Key Laboratory of Virology and Biosafety, RNA Institute, College of Life Sciences and Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China., Wu Z; GemPharmatech Co. Ltd., Nanjing, China., Shi P; GemPharmatech Chengdu Co. Ltd., Chengdu, China., Zhou L; Institute for Vaccine Research at Animal Biosafety Level 3 Laboratory, Wuhan University School of Medicine, Wuhan, China. zhouli_jerry@whu.edu.cn., Chen Y; State Key Laboratory of Virology and Biosafety, RNA Institute, College of Life Sciences and Frontier Science Center for Immunology and Metabolism, Wuhan University, Wuhan, China. chenyu@whu.edu.cn. |
| Source: | Signal transduction and targeted therapy [Signal Transduct Target Ther] 2026 Mar 16; Vol. 11 (1). Date of Electronic Publication: 2026 Mar 16. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Nature Publishing Group Country of Publication: England NLM ID: 101676423 Publication Model: Electronic Cited Medium: Internet ISSN: 2059-3635 (Electronic) Linking ISSN: 20593635 NLM ISO Abbreviation: Signal Transduct Target Ther Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 2059-3635 |
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| DOI: | 10.1038/s41392-026-02640-5 |
