Anxiolytic, anti-depressive and cognition-enhancing effects of total saponins from lily bulbs in ovariectomized mice: A potential therapy for menopause-associated emotional disorders.

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Title: Anxiolytic, anti-depressive and cognition-enhancing effects of total saponins from lily bulbs in ovariectomized mice: A potential therapy for menopause-associated emotional disorders.
Authors: Zhou XD; The Brain Cognition and Brain Disease Institute, Shenzhen Institutes of Advanced Technology, Chinese Academy of Sciences, Shenzhen 518055, Guangdong Province, China; School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong Special Administrative Region 999077, China., Qin ZS; Peking University Clinical Research Institute, Beijing 100191, China., Shi DD; Shanghai Mental Health Center, School of Medicine, Shanghai Jiao Tong University, Shanghai 200030, China., Chiang CY; Digital Centre of State Key Laboratory of Quality Research in Chinese Medicine, Macau University of Science and Technology, Macau 999078, China., Zhang ZJ; School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong Special Administrative Region 999077, China. Electronic address: zhangzj@hku.hk.
Source: Journal of integrative medicine [J Integr Med] 2026 May; Vol. 24 (3), pp. 403-414. Date of Electronic Publication: 2026 Mar 03.
Publication Type: Journal Article
Journal Info: Publisher: Elsevier B.V Country of Publication: Netherlands NLM ID: 101603118 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2095-4964 (Print) NLM ISO Abbreviation: J Integr Med Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2095-4964
DOI:10.1016/j.joim.2025.12.012