Dimethyl Fumarate Reverses β-Adrenoceptor-Mediated Myocardial Fibrosis in Mice by Inhibiting Yes-Associated Protein-Regulated Expression of Intermediate-Conductance Ca2+-Activated K+ Channel in Fibroblasts.

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Title:	Dimethyl Fumarate Reverses β-Adrenoceptor-Mediated Myocardial Fibrosis in Mice by Inhibiting Yes-Associated Protein-Regulated Expression of Intermediate-Conductance Ca²⁺-Activated K⁺ Channel in Fibroblasts.
Authors:	Wu LH; Department of Physiology and Pathophysiology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.; Department of Basic Medicine Xi'an Medical University Xi'an Shaanxi China., Bai RY; Department of Physiology and Pathophysiology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China., Chen JY; School of Pharmacy Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China., Pang ZD; Department of Physiology and Pathophysiology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China., Hai XX; Department of Physiology and Pathophysiology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China., Han MZ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China., Yang YY; Department of Physiology and Pathophysiology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China., Wang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China., Zhang Y; Department of Physiology and Pathophysiology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China., Zhang J; School of Pharmacy Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China., She G; Department of Physiology and Pathophysiology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China., Du XJ; Department of Physiology and Pathophysiology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China., Deng XL; Department of Physiology and Pathophysiology, School of Basic Medical Sciences Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.; Key Laboratory of Environment and Genes Related to Diseases, Ministry of Education Xi'an Jiaotong University Health Science Center Xi'an Shaanxi China.
Source:	Journal of the American Heart Association [J Am Heart Assoc] 2026 Apr 07; Vol. 15 (7), pp. e046565. Date of Electronic Publication: 2026 Mar 18.
Publication Type:	Journal Article
Journal Info:	Publisher: Wiley-Blackwell Country of Publication: England NLM ID: 101580524 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2047-9980 (Electronic) Linking ISSN: 20479980 NLM ISO Abbreviation: J Am Heart Assoc Subsets: MEDLINE
Database:	MEDLINE Ultimate

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ISSN:	2047-9980
DOI:	10.1161/JAHA.125.046565