Early-Onset Digestive System Cancers: Risk Factors and Clinicopathological and Molecular Features Across Organ Sites.
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| Title: | Early-Onset Digestive System Cancers: Risk Factors and Clinicopathological and Molecular Features Across Organ Sites. |
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| Authors: | Nakazawa N; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of General Surgical Science, Gunma University Graduate School of Medicine, Maebashi, Japan., Ugai S; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Division of Integrative Cancer Research, National Cancer Center Research Institute, Tokyo, Japan.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Kondo A; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Division of Integrative Cancer Research, National Cancer Center Research Institute, Tokyo, Japan., Matsuda K; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Division of Integrative Cancer Research, National Cancer Center Research Institute, Tokyo, Japan., Kato S; Division of Integrative Cancer Research, National Cancer Center Research Institute, Tokyo, Japan.; Department of Human Pathology, Graduate School of Medical and Dental Sciences, Institute of Science Tokyo, Tokyo, Japan., Usui G; Department of Quantitative Biomedicine, University of Zurich; Institute for Molecular Health Sciences, ETH Zurich, Zurich, Switzerland., Tanaka S; Division of Prevention, Institute for Cancer Control, National Cancer Center, Tokyo, Japan., Lee HY; Graduate School of Public Health and Healthcare Management, The Catholic University of Korea, Seoul, Republic of Korea.; Catholic Institute for Public Health and Healthcare Management, The Catholic University of Korea, Seoul, Republic of Korea., Zhang X; Channing Division of Network Medicine, Department of Medicine, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA., Miyagawa H; Preventive Medicine and Environmental Health, Graduate School of Medicine, Osaka Metropolitan University, Osaka, Japan., Lau MC; Bioinformatics Institute (BII), Agency for Science, Technology and Research (A* STAR), Singapore, Republic of Singapore.; Singapore Immunology Network (SIgN), agency for Science, Technology and Research (A* STAR), Singapore, Republic of Singapore., Saeki H; Department of General Surgical Science, Gunma University Graduate School of Medicine, Maebashi, Japan., Kanemitsu Y; Department of Colorectal Surgery, National Cancer Center Central Hospital, Tokyo, Japan., Chan AT; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Immunology and Infectious Diseases, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA., Ogino S; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Broad Institute of MIT and Harvard, Cambridge, Massachusetts, USA.; Institute of Science Tokyo, Tokyo, Japan., Song M; Laboratory of Epidemiology and Population Sciences, National Institute on Aging, National Institutes of Health, Baltimore, Maryland, USA., Väyrynen JP; Translational Medicine Research Unit, University of Oulu, Medical Research Center Oulu, and Oulu University Hospital, Oulu, Finland., Ugai T; Department of Pathology, Brigham and Women's Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Division of Integrative Cancer Research, National Cancer Center Research Institute, Tokyo, Japan.; Department of Epidemiology, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA.; Clinical and Translational Epidemiology Unit, Massachusetts General Hospital and Harvard Medical School, Boston, Massachusetts, USA.; Cancer Epidemiology Program, Dana-Farber/Harvard Cancer Center, Boston, Massachusetts, USA.; Zhu Family Center for Global Cancer Prevention, Harvard T.H. Chan School of Public Health, Boston, Massachusetts, USA. |
| Source: | Cancer science [Cancer Sci] 2026 May; Vol. 117 (5), pp. 1223-1234. Date of Electronic Publication: 2026 Mar 18. |
| Publication Type: | Journal Article; Review |
| Journal Info: | Publisher: Wiley Publishing on behalf of the Japanese Cancer Association Country of Publication: England NLM ID: 101168776 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1349-7006 (Electronic) Linking ISSN: 13479032 NLM ISO Abbreviation: Cancer Sci Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1349-7006 |
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| DOI: | 10.1111/cas.70363 |
