Second-line chemotherapy after gemcitabine plus nab-paclitaxel in metastatic pancreatic cancer: comparative outcomes and AI-guided treatment selection.
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| Title: | Second-line chemotherapy after gemcitabine plus nab-paclitaxel in metastatic pancreatic cancer: comparative outcomes and AI-guided treatment selection. |
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| Authors: | Procaccio L; Medical Oncology 1, Veneto Institute of Oncology IOV-IRCCS, Padova, 35128, Italy., Giordano G; Department of Medical and Surgical Sciences, Policlinico Riuniti di Foggia, Unit of Medical Oncology and Biomolecular Therapy and University of Foggia, Foggia, 71122, Italy., Nichetti F; Medical Oncology 1, Veneto Institute of Oncology IOV-IRCCS, Padova, 35128, Italy., Milella M; Division of Oncology, Verona University and Hospital Trust (AOUI Verona), Verona, 37126, Italy.; Section of Innovation Biomedicine-Oncology Area, Department of Engineering for Innovation Medicine (DIMI), University of Verona, Verona, 37134, Italy., Pretta A; Medical Oncology, University Hospital and University of Cagliari, Cagliari, 09124, Italy., Iacono D; Department of Oncology, Academic Hospital of Udine ASUFC, Udine, 33100, Italy., Niger M; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, 20133, Italy., Casalino S; Investigational Cancer Therapeutics Clinical Unit, Azienda Ospedaliera Universitaria Integrata Verona, Verona, 37126, Italy., Vivaldi C; Department of Translational Research and New Technologies in Medicine and Surgery, University of Pisa, Pisa, 56126, Italy.; Unit of Medical Oncology 2, Pisa University Hospital, Pisa, 56124, Italy., De Vita F; Division of Medical Oncology, Department of Precision Medicine, University of Campania 'L. Vanvitelli', Naples, 81100, Italy., Pusceddu V; Medical Oncology, University Hospital and University of Cagliari, Cagliari, 09124, Italy., Landriscina M; Department of Medical and Surgical Sciences, Policlinico Riuniti di Foggia, Unit of Medical Oncology and Biomolecular Therapy and University of Foggia, Foggia, 71122, Italy., Di Paolo G; Medical Oncology 1, Veneto Institute of Oncology IOV-IRCCS, Padova, 35128, Italy., Sperotto S; Medical Oncology 1, Veneto Institute of Oncology IOV-IRCCS, Padova, 35128, Italy., Masucci M; Department of Medical and Surgical Sciences, Policlinico Riuniti di Foggia, Unit of Medical Oncology and Biomolecular Therapy and University of Foggia, Foggia, 71122, Italy., Tortora G; Medical Oncology, Comprehensive Cancer Center, Fondazione Policlinico Universitario Agostino Gemelli, IRCCS, Rome, 00136, Italy.; Medical Oncology, Università Cattolica del Sacro Cuore, Rome, 00168, Italy., Bianco R; Medical Oncology, University of Federico II, Naples, 80138, Italy., Vasile E; Unit of Medical Oncology 2, Pisa University Hospital, Pisa, 56124, Italy., Zaniboni A; Oncology, Fondazione Poliambulanza, Brescia, 25124, Italy., Miceli CC; Division of Medical Oncology, Department of Precision Medicine, University of Campania 'L. Vanvitelli', Naples, 81100, Italy., Ongaro E; Department of Medical Oncology, Centro di Riferimento Oncologico (CRO) IRCCS Aviano, Aviano, 33081, Italy., Giommoni E; Medical Oncology Division, Azienda Ospedaliero-Universitaria Careggi, Firenze, 50134, Italy., Tinè G; Biostatistics for Clinical Research Unit, Epidemiology and Data Science Unit, Fondazione IRCCS Istituto Nazionale dei Tumori di Milano, Milan, 20133, Italy., Barsotti G; Medical Oncology 1, Veneto Institute of Oncology IOV-IRCCS, Padova, 35128, Italy., Marchesi S; Medical Oncology Department, Fondazione IRCCS Istituto Nazionale dei Tumori, Milan, 20133, Italy., Di Marco M; Department of Medical and Surgical Sciences, Alma Mater Studiorum University of Bologna, Bologna, 40126, Italy.; Medical Oncology Unit, IRCSS, Azienda Ospedaliero Universitaria di Bologna, Bologna, 40138, Italy., Ortolani S; Ospedale P. Pederzoli, Casa di cura, Peschiera del Garda, 37019, Italy., Aprile G; Department of Oncology, Academic Hospital of Udine ASUFC, Udine, 33100, Italy., Scartozzi M; Medical Oncology, University Hospital and University of Cagliari, Cagliari, 09124, Italy., Bergamo F; Medical Oncology 1, Veneto Institute of Oncology IOV-IRCCS, Padova, 35128, Italy., Melisi D; Division of Oncology, Verona University and Hospital Trust (AOUI Verona), Verona, 37126, Italy.; Investigational Cancer Therapeutics Clinical Unit, Azienda Ospedaliera Universitaria Integrata Verona, Verona, 37126, Italy.; Digestive Molecular and Clinical Oncology Research Unit, University of Verona, Verona, 37129, Italy., Lonardi S; Medical Oncology 1, Veneto Institute of Oncology IOV-IRCCS, Padova, 35128, Italy. |
| Source: | The oncologist [Oncologist] 2026 Mar 09; Vol. 31 (4). |
| Publication Type: | Journal Article; Observational Study; Comparative Study |
| Journal Info: | Publisher: Oxford University Press Country of Publication: England NLM ID: 9607837 Publication Model: Print Cited Medium: Internet ISSN: 1549-490X (Electronic) Linking ISSN: 10837159 NLM ISO Abbreviation: Oncologist Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1549-490X |
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| DOI: | 10.1093/oncolo/oyag085 |
