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A Brønsted-based deep eutectic solvent as a green catalyst for the sustainable one-pot synthesis of 1,2,4,5-tetrasubstituted imidazole derivatives: in vitro cytotoxicity and in silico binding studies on HepG2 cells.

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Title: A Brønsted-based deep eutectic solvent as a green catalyst for the sustainable one-pot synthesis of 1,2,4,5-tetrasubstituted imidazole derivatives: in vitro cytotoxicity and in silico binding studies on HepG2 cells.
Authors: Ngoc Tran TA; Department of Organic Chemistry, Faculty of Chemistry, University of Science Ho Chi Minh City 700000 Vietnam ngthai@hcmus.edu.vn.; Vietnam National University Ho Chi Minh City 700000 Vietnam., Nguyen LD; Department of Organic Chemistry, Faculty of Chemistry, University of Science Ho Chi Minh City 700000 Vietnam ngthai@hcmus.edu.vn.; Vietnam National University Ho Chi Minh City 700000 Vietnam., Nguyen KN; Department of Organic Chemistry, Faculty of Chemistry, University of Science Ho Chi Minh City 700000 Vietnam ngthai@hcmus.edu.vn.; Vietnam National University Ho Chi Minh City 700000 Vietnam., Dang PH; Department of Organic Chemistry, Faculty of Chemistry, University of Science Ho Chi Minh City 700000 Vietnam ngthai@hcmus.edu.vn.; Vietnam National University Ho Chi Minh City 700000 Vietnam., Nguyen HT; Department of Organic Chemistry, Faculty of Chemistry, University of Science Ho Chi Minh City 700000 Vietnam ngthai@hcmus.edu.vn.; Vietnam National University Ho Chi Minh City 700000 Vietnam.
Source: RSC advances [RSC Adv] 2026 Mar 18; Vol. 16 (17), pp. 15249-15265. Date of Electronic Publication: 2026 Mar 18 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: Royal Society of Chemistry Country of Publication: England NLM ID: 101581657 Publication Model: eCollection Cited Medium: Internet ISSN: 2046-2069 (Electronic) Linking ISSN: 20462069 NLM ISO Abbreviation: RSC Adv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2046-2069
DOI:10.1039/d6ra00422a