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N-Benzyl-tryptamine Derivatives as Serotonin 5-HT2A Receptor (5-HT2AR) Agonists: Focus on Different In Vitro 5-HT2AR Activity Profiles.

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Title: N-Benzyl-tryptamine Derivatives as Serotonin 5-HT2A Receptor (5-HT2AR) Agonists: Focus on Different In Vitro 5-HT2AR Activity Profiles.
Authors: Pottie E; Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent B-9000, Belgium., Vertriest E; Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent B-9000, Belgium., Martínez-Afani D; Chemobiodynamics Laboratory, Department of Chemistry, Faculty of Sciences, University of Chile, Chile 780003 Santiago, Chile.; Faculty of Chemistry and Pharmaceutical Sciences, University of Chile, Chile 780003 Santiago, Chile., Soares BA; Chemobiodynamics Laboratory, Department of Chemistry, Faculty of Sciences, University of Chile, Chile 780003 Santiago, Chile.; Institute of Exact and Technological Sciences, Federal University of Jataí, Jataí 75801615 Goiás, Brazil., Cassels BK; Chemobiodynamics Laboratory, Department of Chemistry, Faculty of Sciences, University of Chile, Chile 780003 Santiago, Chile., Stove CP; Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent B-9000, Belgium.
Source: ACS chemical neuroscience [ACS Chem Neurosci] 2026 Apr 01; Vol. 17 (7), pp. 1256-1268. Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: American Chemical Society Country of Publication: United States NLM ID: 101525337 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1948-7193 (Electronic) Linking ISSN: 19487193 NLM ISO Abbreviation: ACS Chem Neurosci Subsets: MEDLINE
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  Data: <searchLink fieldCode="AU" term="%22Pottie+E%22">Pottie E</searchLink>; Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent B-9000, Belgium.<br /><searchLink fieldCode="AU" term="%22Vertriest+E%22">Vertriest E</searchLink>; Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent B-9000, Belgium.<br /><searchLink fieldCode="AU" term="%22Martínez-Afani+D%22">Martínez-Afani D</searchLink>; Chemobiodynamics Laboratory, Department of Chemistry, Faculty of Sciences, University of Chile, Chile 780003 Santiago, Chile.; Faculty of Chemistry and Pharmaceutical Sciences, University of Chile, Chile 780003 Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Soares+BA%22">Soares BA</searchLink>; Chemobiodynamics Laboratory, Department of Chemistry, Faculty of Sciences, University of Chile, Chile 780003 Santiago, Chile.; Institute of Exact and Technological Sciences, Federal University of Jataí, Jataí 75801615 Goiás, Brazil.<br /><searchLink fieldCode="AU" term="%22Cassels+BK%22">Cassels BK</searchLink>; Chemobiodynamics Laboratory, Department of Chemistry, Faculty of Sciences, University of Chile, Chile 780003 Santiago, Chile.<br /><searchLink fieldCode="AU" term="%22Stove+CP%22">Stove CP</searchLink>; Laboratory of Toxicology, Department of Bioanalysis, Faculty of Pharmaceutical Sciences, Ghent University, Ghent B-9000, Belgium.
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      – TitleFull: N-Benzyl-tryptamine Derivatives as Serotonin 5-HT2A Receptor (5-HT2AR) Agonists: Focus on Different In Vitro 5-HT2AR Activity Profiles.
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