Conformational dynamics of SARS-CoV-2 spike on a membrane reveals the allosteric effects of furin cleavage and the D614G mutation.
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| Title: | Conformational dynamics of SARS-CoV-2 spike on a membrane reveals the allosteric effects of furin cleavage and the D614G mutation. |
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| Authors: | Shoemaker SR; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Luo M; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Dam KA; Gladstone Institute of Virology, San Francisco, CA, USA., Pak JE; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA., Hoffmann MAG; Gladstone Institute of Virology, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, CA, USA., Marqusee S; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA.; Department of Chemistry, University of California, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, CA, USA. |
| Source: | Science advances [Sci Adv] 2026 Mar 20; Vol. 12 (12), pp. eadx5178. Date of Electronic Publication: 2026 Mar 20. |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
| ISSN: | 2375-2548 |
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| DOI: | 10.1126/sciadv.adx5178 |