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Conformational dynamics of SARS-CoV-2 spike on a membrane reveals the allosteric effects of furin cleavage and the D614G mutation.

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Title: Conformational dynamics of SARS-CoV-2 spike on a membrane reveals the allosteric effects of furin cleavage and the D614G mutation.
Authors: Shoemaker SR; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Luo M; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA., Dam KA; Gladstone Institute of Virology, San Francisco, CA, USA., Pak JE; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA., Hoffmann MAG; Gladstone Institute of Virology, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, CA, USA., Marqusee S; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA.; Department of Chemistry, University of California, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, CA, USA.
Source: Science advances [Sci Adv] 2026 Mar 20; Vol. 12 (12), pp. eadx5178. Date of Electronic Publication: 2026 Mar 20.
Publication Type: Journal Article
Journal Info: Publisher: American Association for the Advancement of Science Country of Publication: United States NLM ID: 101653440 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 2375-2548 (Electronic) Linking ISSN: 23752548 NLM ISO Abbreviation: Sci Adv Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: <searchLink fieldCode="AU" term="%22Shoemaker+SR%22">Shoemaker SR</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Luo+M%22">Luo M</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.<br /><searchLink fieldCode="AU" term="%22Dam+KA%22">Dam KA</searchLink>; Gladstone Institute of Virology, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Pak+JE%22">Pak JE</searchLink>; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Hoffmann+MAG%22">Hoffmann MAG</searchLink>; Gladstone Institute of Virology, San Francisco, CA, USA.; Department of Medicine, University of California, San Francisco, CA, USA.<br /><searchLink fieldCode="AU" term="%22Marqusee+S%22">Marqusee S</searchLink>; Department of Molecular and Cell Biology, University of California, Berkeley, CA, USA.; Chan Zuckerberg Biohub-San Francisco, San Francisco, CA, USA.; Department of Chemistry, University of California, Berkeley, CA, USA.; California Institute for Quantitative Biosciences, University of California, Berkeley, CA, USA.
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  Data: <searchLink fieldCode="JN" term="%22101653440%22">Science advances</searchLink> [Sci Adv] 2026 Mar 20; Vol. 12 (12), pp. eadx5178. <i>Date of Electronic Publication: </i>2026 Mar 20.
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              Text: 2026 Mar 20
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