Nivolumab in combination with radiotherapy for unresectable advanced or recurrent gastric cancer (CIRCUIT trial): A 5-year update of the progression-free survival and local control outcomes.

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Title: Nivolumab in combination with radiotherapy for unresectable advanced or recurrent gastric cancer (CIRCUIT trial): A 5-year update of the progression-free survival and local control outcomes.
Authors: Suzuki Y; Department of Radiation Oncology, Fukushima Medical University School of Medicine, Japan. Electronic address: ysuzu@fmu.ac.jp., Yoshida D; Department of Radiation Oncology, Kanagawa Cancer Center, Japan., Mimura K; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan; Department of Blood Transfusion and Transplantation Immunology, Fukushima Medical University School of Medicine, Japan., Ogata T; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan., Yoshimoto Y; Department of Radiation Oncology, Fukushima Medical University School of Medicine, Japan., Katoh H; Department of Radiation Oncology, Kanagawa Cancer Center, Japan., Hanayama H; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan., Machida N; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan., Sato H; Department of Radiation Oncology, Fukushima Medical University School of Medicine, Japan., Saze Z; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan., Yamada T; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan., Inokuchi Y; Department of Gastroenterology, Kanagawa Cancer Center, Japan., Takahashi F; Department of Hygiene and Preventive Medicine, Iwate Medical University, Japan. Electronic address: ftakahas@iwate-med.ac.jp., Oshima T; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan., Kono K; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan.
Source: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2026 Jun; Vol. 219, pp. 111494. Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8407192 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0887 (Electronic) Linking ISSN: 01678140 NLM ISO Abbreviation: Radiother Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1879-0887
DOI:10.1016/j.radonc.2026.111494