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Nivolumab in combination with radiotherapy for unresectable advanced or recurrent gastric cancer (CIRCUIT trial): A 5-year update of the progression-free survival and local control outcomes.

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Title: Nivolumab in combination with radiotherapy for unresectable advanced or recurrent gastric cancer (CIRCUIT trial): A 5-year update of the progression-free survival and local control outcomes.
Authors: Suzuki Y; Department of Radiation Oncology, Fukushima Medical University School of Medicine, Japan. Electronic address: ysuzu@fmu.ac.jp., Yoshida D; Department of Radiation Oncology, Kanagawa Cancer Center, Japan., Mimura K; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan; Department of Blood Transfusion and Transplantation Immunology, Fukushima Medical University School of Medicine, Japan., Ogata T; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan., Yoshimoto Y; Department of Radiation Oncology, Fukushima Medical University School of Medicine, Japan., Katoh H; Department of Radiation Oncology, Kanagawa Cancer Center, Japan., Hanayama H; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan., Machida N; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan., Sato H; Department of Radiation Oncology, Fukushima Medical University School of Medicine, Japan., Saze Z; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan., Yamada T; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan., Inokuchi Y; Department of Gastroenterology, Kanagawa Cancer Center, Japan., Takahashi F; Department of Hygiene and Preventive Medicine, Iwate Medical University, Japan. Electronic address: ftakahas@iwate-med.ac.jp., Oshima T; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan., Kono K; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan.
Source: Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2026 Jun; Vol. 219, pp. 111494. Date of Electronic Publication: 2026 Mar 19.
Publication Type: Journal Article; Clinical Trial, Phase II; Clinical Trial, Phase I
Journal Info: Publisher: Elsevier Scientific Publishers Country of Publication: Ireland NLM ID: 8407192 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1879-0887 (Electronic) Linking ISSN: 01678140 NLM ISO Abbreviation: Radiother Oncol Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: Nivolumab in combination with radiotherapy for unresectable advanced or recurrent gastric cancer (CIRCUIT trial): A 5-year update of the progression-free survival and local control outcomes.
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  Data: <searchLink fieldCode="AU" term="%22Suzuki+Y%22">Suzuki Y</searchLink>; Department of Radiation Oncology, Fukushima Medical University School of Medicine, Japan. Electronic address: ysuzu@fmu.ac.jp.<br /><searchLink fieldCode="AU" term="%22Yoshida+D%22">Yoshida D</searchLink>; Department of Radiation Oncology, Kanagawa Cancer Center, Japan.<br /><searchLink fieldCode="AU" term="%22Mimura+K%22">Mimura K</searchLink>; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan; Department of Blood Transfusion and Transplantation Immunology, Fukushima Medical University School of Medicine, Japan.<br /><searchLink fieldCode="AU" term="%22Ogata+T%22">Ogata T</searchLink>; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan.<br /><searchLink fieldCode="AU" term="%22Yoshimoto+Y%22">Yoshimoto Y</searchLink>; Department of Radiation Oncology, Fukushima Medical University School of Medicine, Japan.<br /><searchLink fieldCode="AU" term="%22Katoh+H%22">Katoh H</searchLink>; Department of Radiation Oncology, Kanagawa Cancer Center, Japan.<br /><searchLink fieldCode="AU" term="%22Hanayama+H%22">Hanayama H</searchLink>; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan.<br /><searchLink fieldCode="AU" term="%22Machida+N%22">Machida N</searchLink>; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan.<br /><searchLink fieldCode="AU" term="%22Sato+H%22">Sato H</searchLink>; Department of Radiation Oncology, Fukushima Medical University School of Medicine, Japan.<br /><searchLink fieldCode="AU" term="%22Saze+Z%22">Saze Z</searchLink>; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan.<br /><searchLink fieldCode="AU" term="%22Yamada+T%22">Yamada T</searchLink>; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan.<br /><searchLink fieldCode="AU" term="%22Inokuchi+Y%22">Inokuchi Y</searchLink>; Department of Gastroenterology, Kanagawa Cancer Center, Japan.<br /><searchLink fieldCode="AU" term="%22Takahashi+F%22">Takahashi F</searchLink>; Department of Hygiene and Preventive Medicine, Iwate Medical University, Japan. Electronic address: ftakahas@iwate-med.ac.jp.<br /><searchLink fieldCode="AU" term="%22Oshima+T%22">Oshima T</searchLink>; Department of Gastroenterological Surgery, Kanagawa Cancer Center, Japan.<br /><searchLink fieldCode="AU" term="%22Kono+K%22">Kono K</searchLink>; Department of Gastrointestinal Tract Surgery, Fukushima Medical University School of Medicine, Japan.
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  Data: <searchLink fieldCode="JN" term="%228407192%22">Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology</searchLink> [Radiother Oncol] 2026 Jun; Vol. 219, pp. 111494. <i>Date of Electronic Publication: </i>2026 Mar 19.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Elsevier+Scientific+Publishers%22">Elsevier Scientific Publishers </searchLink><i>Country of Publication: </i>Ireland <i>NLM ID: </i>8407192 <i>Publication Model: </i>Print-Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1879-0887 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2201678140%22">01678140 </searchLink><i>NLM ISO Abbreviation: </i>Radiother Oncol <i>Subsets: </i>MEDLINE
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        Value: 10.1016/j.radonc.2026.111494
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              M: 06
              Text: 2026 Jun
              Type: published
              Y: 2026
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