Divalent siRNA for prion disease.

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Title: Divalent siRNA for prion disease.
Authors: Gentile JE; Program in Brain Health, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Corridon TL; Program in Brain Health, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Serack FE; Program in Brain Health, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Echeverria D; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, 01655, USA., Kennedy ZC; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, 01655, USA., Gallant-Behm CL; Atalanta Therapeutics, Boston, MA, 02210, USA., Hassler MR; Atalanta Therapeutics, Boston, MA, 02210, USA., Kinberger GA; Atalanta Therapeutics, Boston, MA, 02210, USA., Kelemen MN; Program in Brain Health, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Kamath NG; Program in Brain Health, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Lian Y; Program in Brain Health, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Gross KY; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, 01655, USA., Miller R; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, 01655, USA., DeSouza-Lenz K; Comparative Medicine, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Howard M; Comparative Medicine, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Guzman K; Comparative Medicine, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Chan N; Comparative Medicine, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Laversenne V; Program in Brain Health, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Curtis DT; Atalanta Therapeutics, Boston, MA, 02210, USA., Fettes K; FTS Pharma Consulting LLC, Medfield, MA, 02052, USA., Lemaitre M; ML Consult LLC., Jackson AL; Atalanta Therapeutics, Boston, MA, 02210, USA., Yamada K; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, 01655, USA., Alterman JF; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, 01655, USA., Coffey AA; Program in Brain Health, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA., Minikel EV; Program in Brain Health, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; McCance Center for Brain Health and Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.; Department of Neurology, Harvard Medical School, Boston, MA, 02115, USA.; Prion Alliance, Cambridge, MA, 02139, USA., Khvorova A; RNA Therapeutics Institute, UMass Chan Medical School, Worcester, MA, 01655, USA., Vallabh SM; Program in Brain Health, Broad Institute of MIT and Harvard, Cambridge, MA, 02142, USA.; McCance Center for Brain Health and Department of Neurology, Massachusetts General Hospital, Boston, MA, 02114, USA.; Department of Neurology, Harvard Medical School, Boston, MA, 02115, USA.; Prion Alliance, Cambridge, MA, 02139, USA.
Source: BioRxiv : the preprint server for biology [bioRxiv] 2026 Mar 05. Date of Electronic Publication: 2026 Mar 05.
Publication Type: Journal Article; Preprint
Journal Info: Country of Publication: United States NLM ID: 101680187 Publication Model: Electronic Cited Medium: Internet ISSN: 2692-8205 (Electronic) Linking ISSN: 26928205 NLM ISO Abbreviation: bioRxiv Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2692-8205
DOI:10.1101/2024.12.05.627039