IFNγ-associated immune-metabolic remodeling is linked to serotonin-kynurenine imbalance and cortical vulnerability in lupus-prone mice.
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| Title: | IFNγ-associated immune-metabolic remodeling is linked to serotonin-kynurenine imbalance and cortical vulnerability in lupus-prone mice. |
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| Authors: | Matmat K; Inserm - Centre d'Investigation Clinique 1434, Neuroprotection and Remyelination - Centre de Recherche en Biomédecine de Strasbourg, University of Strasbourg, Strasbourg, France., Guéant-Rodriguez RM; Lorraine University, CHRU Nancy, Department of Biochemistry, Molecular Biology, Nutrition; Inserm 1256-NGERE, F-54000, Nancy, France.; Reference Center of Inborn Errors of Metabolism - CHRU Nancy, Nancy, France., Darcq E; Inserm - Unité Mixte de Recherche en Santé (UMRS) 1329, Strasbourg Translational Neuroscience and Psychiatry - University of Strasbourg, Strasbourg, France., Baspinar O; Lorraine University, CHRU Nancy, Department of Biochemistry, Molecular Biology, Nutrition; Inserm 1256-NGERE, F-54000, Nancy, France., Alberto JM; Lorraine University, CHRU Nancy, Department of Biochemistry, Molecular Biology, Nutrition; Inserm 1256-NGERE, F-54000, Nancy, France., Guéant JL; Reference Center of Inborn Errors of Metabolism - CHRU Nancy, Nancy, France.; Institute of Medical Research (Pôle BMS), University of Lorraine, Nancy, France.; Joan Klein Jacobs Center for Precision Nutrition and Health, Cornell University, Ithaca, NY, United States., Mensah-Nyagan AG; Inserm - Centre d'Investigation Clinique 1434, Neuroprotection and Remyelination - Centre de Recherche en Biomédecine de Strasbourg, University of Strasbourg, Strasbourg, France., Jeltsch-David H; Laboratoire des Sciences de l'Ingénieur, de l'Informatique et de l'Imagerie ICube, Unité Mixte de Recherche (UMR) 7357, Centre National de la Recherche Scientifique (CNRS)/Université de Strasbourg/Institut National des Sciences Appliquées (INSA)/École Nationale du Génie de l'Eau et de l'Environnement de Strasbourg (ENGEES)/Institut National de Recherche en Informatique et en Automatique (INRIA), Strasbourg, France. |
| Source: | Frontiers in immunology [Front Immunol] 2026 Mar 05; Vol. 17, pp. 1740039. Date of Electronic Publication: 2026 Mar 05 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2026.1740039 |
