Renal macrophage TLR7 signaling in lupus nephritis: from pathogenic mechanisms to therapeutic opportunities.

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Title: Renal macrophage TLR7 signaling in lupus nephritis: from pathogenic mechanisms to therapeutic opportunities.
Authors: Li L; Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, National Clinical Key Specialty Construction Program (2023), Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Lin Z; Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, National Clinical Key Specialty Construction Program (2023), Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Chen L; Department of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Huang J; Department of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Luo H; Department of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Bi Z; Department of Computer and Information Technology, Purdue Polytechnic Institute, Purdue University, West Lafayette, IN, United States., Wang T; School of Advanced Technology, Xi'an Jiaotong-Liverpool University, Suzhou, Jiangsu, China., Xu Y; Department of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Liu H; Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, National Clinical Key Specialty Construction Program (2023), Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Hao J; Department of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China., Qi J; Guangdong Provincial Key Laboratory of Autophagy and Major Chronic Non-Communicable Diseases, National Clinical Key Specialty Construction Program (2023), Institute of Nephrology, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.; Key Laboratory of Prevention and Management of Chronic Kidney Disease of Zhanjiang City, Affiliated Hospital of Guangdong Medical University, Zhanjiang, Guangdong, China.
Source: Frontiers in immunology [Front Immunol] 2026 Mar 05; Vol. 17, pp. 1776348. Date of Electronic Publication: 2026 Mar 05 (Print Publication: 2026).
Publication Type: Journal Article; Review
Journal Info: Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE; In Process
Database: MEDLINE Ultimate
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ISSN:1664-3224
DOI:10.3389/fimmu.2026.1776348