MYCN inhibits TrkC-mediated differentiation in neuroblastoma cells via disruption of the PKA signalling pathway.

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Title: MYCN inhibits TrkC-mediated differentiation in neuroblastoma cells via disruption of the PKA signalling pathway.
Authors: Maher S; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland., Roe A; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland., Wynne K; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland.; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland., Zhernovkov V; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland., Halasz M; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland. melinda.halasz@ucd.ie.; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland. melinda.halasz@ucd.ie.
Source: Cell death discovery [Cell Death Discov] 2026 Mar 25; Vol. 12 (1). Date of Electronic Publication: 2026 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2058-7716
DOI:10.1038/s41420-026-03024-y