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MYCN inhibits TrkC-mediated differentiation in neuroblastoma cells via disruption of the PKA signalling pathway.

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Title: MYCN inhibits TrkC-mediated differentiation in neuroblastoma cells via disruption of the PKA signalling pathway.
Authors: Maher S; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland., Roe A; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland., Wynne K; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland.; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland., Zhernovkov V; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland., Halasz M; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland. melinda.halasz@ucd.ie.; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland. melinda.halasz@ucd.ie.
Source: Cell death discovery [Cell Death Discov] 2026 Mar 25; Vol. 12 (1). Date of Electronic Publication: 2026 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: Nature Publishing Group Country of Publication: United States NLM ID: 101665035 Publication Model: Electronic Cited Medium: Print ISSN: 2058-7716 (Print) Linking ISSN: 20587716 NLM ISO Abbreviation: Cell Death Discov Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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  Data: MYCN inhibits TrkC-mediated differentiation in neuroblastoma cells via disruption of the PKA signalling pathway.
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  Data: <searchLink fieldCode="AU" term="%22Maher+S%22">Maher S</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland.<br /><searchLink fieldCode="AU" term="%22Roe+A%22">Roe A</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland.<br /><searchLink fieldCode="AU" term="%22Wynne+K%22">Wynne K</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland.; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland.<br /><searchLink fieldCode="AU" term="%22Zhernovkov+V%22">Zhernovkov V</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland.<br /><searchLink fieldCode="AU" term="%22Halasz+M%22">Halasz M</searchLink>; Systems Biology Ireland, School of Medicine, University College Dublin, Belfield, Ireland. melinda.halasz@ucd.ie.; Conway Institute of Biomolecular and Biomedical Research, University College Dublin, Belfield, Ireland. melinda.halasz@ucd.ie.
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  Data: <searchLink fieldCode="JN" term="%22101665035%22">Cell death discovery</searchLink> [Cell Death Discov] 2026 Mar 25; Vol. 12 (1). <i>Date of Electronic Publication: </i>2026 Mar 25.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22Nature+Publishing+Group%22">Nature Publishing Group </searchLink><i>Country of Publication: </i>United States <i>NLM ID: </i>101665035 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Print <i>ISSN: </i>2058-7716 (Print) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2220587716%22">20587716 </searchLink><i>NLM ISO Abbreviation: </i>Cell Death Discov <i>Subsets: </i>PubMed not MEDLINE
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        Value: 10.1038/s41420-026-03024-y
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      – Code: eng
        Text: English
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              Text: 2026 Mar 25
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