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Tau catalyzes amyloid-β aggregation and toxicity in a polymorph-dependent manner.

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Bibliographic Details
Title: Tau catalyzes amyloid-β aggregation and toxicity in a polymorph-dependent manner.
Authors: Mosconi M; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri Scientific Institutes for Research, Hospitalization and Healthcare, Milano 20156, Italy., Leonardi C; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri Scientific Institutes for Research, Hospitalization and Healthcare, Milano 20156, Italy., Armour-Garb Z; Center for Misfolding Diseases, Yusuf Hamied Department of Chemistry, Cambridge University, Cambridge CB2 1EW, United Kingdom., Rocutto B; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri Scientific Institutes for Research, Hospitalization and Healthcare, Milano 20156, Italy., Beeg M; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri Scientific Institutes for Research, Hospitalization and Healthcare, Milano 20156, Italy., Meisl G; Center for Misfolding Diseases, Yusuf Hamied Department of Chemistry, Cambridge University, Cambridge CB2 1EW, United Kingdom., Ortigosa-Pascual L; Biochemistry and Structural Biology, Department of Chemistry, Lund University, Lund 223 62, Sweden., Broggini L; Department of Biosciences, Università degli Studi di Milano, Milano 20133, Italy., Salmona M; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri Scientific Institutes for Research, Hospitalization and Healthcare, Milano 20156, Italy., Ricagno S; Department of Biosciences, Università degli Studi di Milano, Milano 20133, Italy., Knowles TPJ; Center for Misfolding Diseases, Yusuf Hamied Department of Chemistry, Cambridge University, Cambridge CB2 1EW, United Kingdom., Diomede L; Department of Molecular Biochemistry and Pharmacology, Istituto di Ricerche Farmacologiche Mario Negri Scientific Institutes for Research, Hospitalization and Healthcare, Milano 20156, Italy.
Source: Proceedings of the National Academy of Sciences of the United States of America [Proc Natl Acad Sci U S A] 2026 Mar 31; Vol. 123 (13), pp. e2532775123. Date of Electronic Publication: 2026 Mar 25.
Publication Type: Journal Article
Journal Info: Publisher: National Academy of Sciences Country of Publication: United States NLM ID: 7505876 Publication Model: Print-Electronic Cited Medium: Internet ISSN: 1091-6490 (Electronic) Linking ISSN: 00278424 NLM ISO Abbreviation: Proc Natl Acad Sci U S A Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:1091-6490
DOI:10.1073/pnas.2532775123