Symptom relief and cytokine modulation by clarithromycin in mild COVID-19 pneumonia: an exploratory, multicenter, randomized-controlled open-label trial (CAME-COVID study).

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Title: Symptom relief and cytokine modulation by clarithromycin in mild COVID-19 pneumonia: an exploratory, multicenter, randomized-controlled open-label trial (CAME-COVID study).
Authors: Yamamoto K; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan.; First Department of Internal Medicine, Division of Infectious, Respiratory, and Digestive Medicine, University of the Ryukyus Graduate School of Medicine, Kiyuna 1076, Ginowan, Okinawa 901-2720, Japan., Iwanaga N; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan., Umemura A; Department of Respiratory Medicine, Sasebo City General Hospital, Sasebo, Nagasaki, Japan., Sawai T; Department of Respiratory Medicine, Nagasaki Harbor Medical Center, Nagasaki, Nagasaki, Japan., Sumiyoshi M; Department of Respiratory Medicine, Japan Community Health Care Organization JCHO Isahaya General Hospital, Isahaya, Nagasaki, Japan., Hashiguchi K; Department of Respiratory Medicine, Japanese Red Cross Nagasaki Genbaku Hospital, Nagasaki, Nagasaki, Japan., Mori Y; Department of Respiratory Medicine, Kitakyusyu City Yahata Hospital, Kitakyusyu, Fukuoka, Japan., Ishii H; Department of Respiratory Medicine, Fukuoka University Chikushi Hospital, Chikushino, Fukuoka, Japan., Futsuki Y; Department of Respiratory Medicine, Saiseikai Nagasaki Hospital, Nagasaki, Nagasaki, Japan., Kiyohara M; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan., Ota K; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan., Kosai K; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan., Sasaki D; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan., Takamatsu Y; Department of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Nagasaki, Japan., Inoue S; Department of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Nagasaki, Japan., Morita K; Department of Virology, Institute of Tropical Medicine, Nagasaki University, Nagasaki, Nagasaki, Japan., Tsutsui S; Department of Radiology, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan., Ashizawa K; Department of Clinical Oncology, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan., Takazono T; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan., Sakamoto N; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan., Hosogaya N; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan., Tashiro M; Infection Control and Education Center, Department of Infectious Diseases, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan.; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan., Tanaka T; Infection Control and Education Center, Department of Infectious Diseases, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan., Izumikawa K; Department of Infectious Diseases, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan., Yanagihara K; Department of Laboratory Medicine, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Nagasaki, Japan., Mukae H; Department of Respiratory Medicine, Nagasaki University Hospital, Nagasaki, Nagasaki, Japan.
Source: Therapeutic advances in infectious disease [Ther Adv Infect Dis] 2026 Mar 15; Vol. 13, pp. 20499361261431488. Date of Electronic Publication: 2026 Mar 15 (Print Publication: 2026).
Publication Type: Journal Article
Journal Info: Publisher: SAGE Publications Country of Publication: England NLM ID: 101606715 Publication Model: eCollection Cited Medium: Print ISSN: 2049-9361 (Print) Linking ISSN: 20499361 NLM ISO Abbreviation: Ther Adv Infect Dis Subsets: PubMed not MEDLINE
Database: MEDLINE Ultimate
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ISSN:2049-9361
DOI:10.1177/20499361261431488