Prospective randomised trial comparing thermal ablation With laparoscopic Adrenalectomy as an alternatiVE treatment for unilateral asymmetric primary aldosteronism: a protocol for the WAVE trial.

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Title: Prospective randomised trial comparing thermal ablation With laparoscopic Adrenalectomy as an alternatiVE treatment for unilateral asymmetric primary aldosteronism: a protocol for the WAVE trial.
Authors: Laycock K; Queen Mary University of London, London, UK kate.laycock@nhs.net.; St Bartholomew's Hospital, London, England, UK., Kearney J; Queen Mary University of London, London, UK.; St Bartholomew's Hospital, London, England, UK.; Endocrinology ASO/EASO COM, King's College Hospital NHS Trust, London, UK., Lee YN; Queen Mary University of London, London, UK.; St Bartholomew's Hospital, London, England, UK., Macfarlane J; Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, UK., Goodchild E; Queen Mary University of London, London, UK.; St Bartholomew's Hospital, London, England, UK., Ng E; St Bartholomew's Hospital, London, England, UK., Pineau Mitchell A; Queen Mary University of London, London, UK.; St Bartholomew's Hospital, London, England, UK., Wu X; Queen Mary University of London, London, UK.; St Bartholomew's Hospital, London, England, UK., Htut Z; Imperial College London, London, England, UK., Goodchild G; Gastroenterology, St Bartholomew's Hospital, London, England, UK., Lowe D; The Royal London Hospital, London, England, UK., Hilliard N; Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, UK., Godfrey E; Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, UK., Qazi N; Imperial College London, London, England, UK., Bastos J; The Royal London Hospital, London, England, UK., Chua A; St Bartholomew's Hospital, London, England, UK., Mahroof R; Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, UK., Palma A; Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, UK., Khatun A; Queen Mary University of London, London, UK.; St Bartholomew's Hospital, London, England, UK., Varsani C; St Bartholomew's Hospital, London, England, UK., Benu D; Queen Mary University of London, London, UK.; St Bartholomew's Hospital, London, England, UK., Pereira SP; Institute for Liver and Digestive Health, University College London, London, UK., Krishnamurthy M; Nuclear Medicine, St Bartholomew's Hospital, London, England, UK., Cheow H; Nuclear Medicine, Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, UK., Chung TT; Endocrine, University College London, London, England, UK., Carroll P; Endocrine, Guy's and St Thomas' Hospitals NHS Trust, London, England, UK., O'Toole S; Sheffield Teaching Hospitals NHS Foundation Trust, Sheffield, England, UK., Wernig F; Imperial College London, London, England, UK., Gurnell M; Cambridge University Hospitals NHS Foundation Trust, Cambridge, England, UK., Brown M; Queen Mary University of London, London, UK.; St Bartholomew's Hospital, London, England, UK., Drake WM; Queen Mary University of London, London, UK.; St Bartholomew's Hospital, London, England, UK.
Source: BMJ open [BMJ Open] 2026 Mar 26; Vol. 16 (3), pp. e111798. Date of Electronic Publication: 2026 Mar 26.
Publication Type: Journal Article; Clinical Trial Protocol
Journal Info: Publisher: BMJ Publishing Group Ltd Country of Publication: England NLM ID: 101552874 Publication Model: Electronic Cited Medium: Internet ISSN: 2044-6055 (Electronic) Linking ISSN: 20446055 NLM ISO Abbreviation: BMJ Open Subsets: MEDLINE
Database: MEDLINE Ultimate
Description
ISSN:2044-6055
DOI:10.1136/bmjopen-2025-111798