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CPNE1: A novel therapeutic target for myopia progression - from genetic GWAS discovery to functional validation in vitro and vivo.

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Title: CPNE1: A novel therapeutic target for myopia progression - from genetic GWAS discovery to functional validation in vitro and vivo.
Authors: Jia L; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China., Wei P; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China.; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, People's Republic Of China., Wang Y; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China., Xia Z; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China., Gao S; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China., Wang Y; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China. wangyan7143@vip.sina.com.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China. wangyan7143@vip.sina.com.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China. wangyan7143@vip.sina.com.; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, People's Republic Of China. wangyan7143@vip.sina.com., Han G; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China. dovehanguoge@hotmail.com.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China. dovehanguoge@hotmail.com.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China. dovehanguoge@hotmail.com.; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, People's Republic Of China. dovehanguoge@hotmail.com.
Source: Journal of translational medicine [J Transl Med] 2026 Mar 26; Vol. 24 (1). Date of Electronic Publication: 2026 Mar 26.
Publication Type: Journal Article; Meta-Analysis
Journal Info: Publisher: BioMed Central Country of Publication: England NLM ID: 101190741 Publication Model: Electronic Cited Medium: Internet ISSN: 1479-5876 (Electronic) Linking ISSN: 14795876 NLM ISO Abbreviation: J Transl Med Subsets: MEDLINE
Database: MEDLINE Ultimate
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  Data: CPNE1: A novel therapeutic target for myopia progression - from genetic GWAS discovery to functional validation in vitro and vivo.
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  Data: <searchLink fieldCode="AU" term="%22Jia+L%22">Jia L</searchLink>; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China.<br /><searchLink fieldCode="AU" term="%22Wei+P%22">Wei P</searchLink>; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China.; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, People's Republic Of China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China.<br /><searchLink fieldCode="AU" term="%22Xia+Z%22">Xia Z</searchLink>; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China.<br /><searchLink fieldCode="AU" term="%22Gao+S%22">Gao S</searchLink>; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China.<br /><searchLink fieldCode="AU" term="%22Wang+Y%22">Wang Y</searchLink>; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China. wangyan7143@vip.sina.com.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China. wangyan7143@vip.sina.com.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China. wangyan7143@vip.sina.com.; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, People's Republic Of China. wangyan7143@vip.sina.com.<br /><searchLink fieldCode="AU" term="%22Han+G%22">Han G</searchLink>; Tianjin Eye Hospital, Tianjin Key Lab of Ophthalmology and Visual Science, Tianjin, 300020, PR China. dovehanguoge@hotmail.com.; Nankai University Affiliated Tianjin Eye Hospital, Nankai University Optometry and Vision Sicence Insitute, Tianjin, 300020, PR China. dovehanguoge@hotmail.com.; Nankai University Eye Institute, Nankai University, Tianjin, 300020, PR China. dovehanguoge@hotmail.com.; Clinical College of Ophthalmology, Tianjin Medical University, Tianjin, 300020, People's Republic Of China. dovehanguoge@hotmail.com.
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  Data: <searchLink fieldCode="JN" term="%22101190741%22">Journal of translational medicine</searchLink> [J Transl Med] 2026 Mar 26; Vol. 24 (1). <i>Date of Electronic Publication: </i>2026 Mar 26.
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  Data: <i>Publisher: </i><searchLink fieldCode="PB" term="%22BioMed+Central%22">BioMed Central </searchLink><i>Country of Publication: </i>England <i>NLM ID: </i>101190741 <i>Publication Model: </i>Electronic <i>Cited Medium: </i>Internet <i>ISSN: </i>1479-5876 (Electronic) <i>Linking ISSN: </i><searchLink fieldCode="IS" term="%2214795876%22">14795876 </searchLink><i>NLM ISO Abbreviation: </i>J Transl Med <i>Subsets: </i>MEDLINE
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      – TitleFull: CPNE1: A novel therapeutic target for myopia progression - from genetic GWAS discovery to functional validation in vitro and vivo.
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            NameFull: Jia L
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            – D: 26
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              Text: 2026 Mar 26
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              Y: 2026
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