Midgestational injection of highly expanded human CD34+ cells increases lineages of human immune cells and supports thymic development in RAG2-/-IL2RG-/Y SCID pigs.
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| Title: | Midgestational injection of highly expanded human CD34+ cells increases lineages of human immune cells and supports thymic development in RAG2-/-IL2RG-/Y SCID pigs. |
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| Authors: | Forster AM; Department of Animal Science, Iowa State University, Ames, IA, United States., Kress AA; Laboratory Animal Resources, Iowa State University, Ames, IA, United States., Kiupel M; Department of Pathobiology and Diagnostic Investigation, College of Veterinary Medicine, Michigan State University, East Lansing, MI, United States., Cunnick J; Department of Animal Science, Iowa State University, Ames, IA, United States., Webster DA; Recombinetics, Inc., New Brighton, MN, United States., Campbell JM; Recombinetics, Inc., New Brighton, MN, United States., Watson AL; Recombinetics, Inc., New Brighton, MN, United States., Gafni O; Recombinetics, Inc., New Brighton, MN, United States., Carlson DF; Recombinetics, Inc., New Brighton, MN, United States., Moriarity BS; Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States., Webber BR; Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States., Napiwocki B; Department of Pediatrics, University of Minnesota, Minneapolis, MN, United States., Daharsh L; Department of Animal Science, Iowa State University, Ames, IA, United States., Ross JW; Department of Animal Science, Iowa State University, Ames, IA, United States., Sauer MB; Laboratory Animal Resources, Iowa State University, Ames, IA, United States., Tuggle CK; Department of Animal Science, Iowa State University, Ames, IA, United States. |
| Source: | Frontiers in immunology [Front Immunol] 2026 Mar 11; Vol. 17, pp. 1751541. Date of Electronic Publication: 2026 Mar 11 (Print Publication: 2026). |
| Publication Type: | Journal Article |
| Journal Info: | Publisher: Frontiers Research Foundation] Country of Publication: Switzerland NLM ID: 101560960 Publication Model: eCollection Cited Medium: Internet ISSN: 1664-3224 (Electronic) Linking ISSN: 16643224 NLM ISO Abbreviation: Front Immunol Subsets: MEDLINE |
| Database: | MEDLINE Ultimate |
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| ISSN: | 1664-3224 |
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| DOI: | 10.3389/fimmu.2026.1751541 |
